Lymphoproliferative Disease with Features of Lymphoma in the Central Nervous System of a Horse

被引：12

作者：

Morrison, L. R. ^{[1
]}

Freel, K. ^{[1
]}

Henderson, I. ^{[2
]}

Hahn, C. ^{[2
]}

Smith, S. H. ^{[1
]}

机构：

[1] Univ Edinburgh, Easter Bush Vet Ctr, Vet Pathol Unit, Roslin EH25 9RG, Midlothian, Scotland

[2] Univ Edinburgh, Easter Bush Vet Ctr, Dept Vet Clin Studies, Royal Dick Sch Vet Studies, Roslin EH25 9RG, Midlothian, Scotland

来源：

JOURNAL OF COMPARATIVE PATHOLOGY | 2008年 / 139卷 / 04期

关键词：

central nervous system; horse; immunohistochemistry; lymphoma; lymphoproliferative;

D O I：

10.1016/j.jcpa.2008.07.008

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Lymphoma (malignant lymphoma, lymphosarcoma) is uncommon in horses in the United Kingdom. This report describes an unusual form of lymphoproliferative disease with features of lymphoma restricted to the central nervous system (CNS) and with no evidence of a primary lesion elsewhere. Immunohistochemical examination defined an overwhelming predominance of T lymphocytes with admixed B lymphocytes and activated macrophages. This case exemplifies the challenges associated with definitive diagnosis of lymphoproliferative disease of the equine CNS. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：256 / 261

页数：6

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