CNTRICS Final Task Selection: Control of Attention

被引:65
作者
Nuechterlein, Keith H. [1 ,2 ]
Luck, Steven J. [3 ,4 ]
Lustig, Cindy [5 ]
Sarter, Martin [5 ]
机构
[1] Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90024 USA
[3] Univ Calif Davis, Ctr Mind & Brain, Davis, CA 95616 USA
[4] Univ Calif Davis, Dept Psychol, Davis, CA 95616 USA
[5] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA
关键词
PREFRONTAL ACETYLCHOLINE-RELEASE; CONSENSUS COGNITIVE BATTERY; VISUAL-SEARCH; TOP-DOWN; BEHAVIORAL VIGILANCE; SUSTAINED ATTENTION; BASAL FOREBRAIN; GUIDED SEARCH; ANIMAL-MODEL; NEURAL BASIS;
D O I
10.1093/schbul/sbn158
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The construct of attention has many facets that have been examined in human and animal research and in healthy and psychiatrically disordered conditions. The Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) group concluded that control of attention-025EFthe processes that guide selection of task-relevant inputs-025EFis particularly impaired in schizophrenia and could profit from further work with refined measurement tools. Thus, nominations for cognitive tasks that provide discrete measures of control of attention were sought and were then evaluated at the third CNTRICS meeting for their promise for future use in treatment development. This article describes the 5 nominated measures and their strengths and weaknesses for cognitive neuroscience work relevant to treatment development. Two paradigms, Guided Search and the Distractor Condition Sustained Attention Task, were viewed as having the greatest immediate promise for development into tools for treatment research in schizophrenia and are described in more detail by their nominators.
引用
收藏
页码:182 / 196
页数:15
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