Baseline brain perfusion and working memory capacity: a neuroimaging study

被引：8

作者：

Beschoner, Petra ^{[1
]}

Richter, Sven ^{[1
]}

Lo, Hanna ^{[1
]}

Sim, Eun-Jin ^{[1
]}

Baron, Katja ^{[1
]}

Osterfeld, Nadine ^{[1
]}

Horn, Andrea B. ^{[1
,2
]}

Viviani, Roberto ^{[1
,3
]}

机构：

[1] Univ Ulm, Dept Psychiat 3, D-89075 Ulm, Germany

[2] Univ Fribourg, NCCR Affect Sci, Dept Clin Psychol, CH-1700 Fribourg, Switzerland

[3] Univ Bern, Univ Hosp Clin Psychiat, Dept Psychiat, CH-3012 Bern, Switzerland

来源：

NEUROREPORT | 2008年 / 19卷 / 18期

关键词：

arterial spin labeling; baseline brain perfusion; intellectual capacity; working memory capacity;

D O I：

10.1097/WNR.0b013e32831997f1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Early studies of rest cerebral metabolism and perfusion reported no association with intellectual capacity. We revisit this issue using a larger sample (N=146) and a continuous arterial spin labeling technique to measure perfusion, and working memory capacity as a measure of intellectual capacity. In the cortex, working memory capacity correlated diffusely and negatively with perfusion. This negative association was more marked in the prefrontal and temporal cortex of the left hemisphere. However, there were also weak positive correlations in the auditory areas, accompanied by analogous correlations in all other areas associated with sensory modalities, with a preference for right lateralization. These findings are discussed in terms of the cortical and vascular organization of the brain. NeuroReport 19:1803-1807 (C) 2008 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

引用

页码：1803 / 1807

页数：5

共 25 条

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