Synthesis and Application of Water-Soluble Conjugated Glycopolymer

被引：0
作者：
Sun Pengfei [1 ,2 ,3 ]
Hou Huanzhi [1 ,2 ]
Fan Quli [1 ,2 ]
Huang Wei [1 ,2 ,4 ,5 ]
机构：
[1] Nanjing Univ Posts & Telecommun, Jiangsu Synerget Innovat Ctr Adv Mat, Key Lab Organ Elect & Informat Displays, Nanjing 210023, Jiangsu, Peoples R China
[2] Nanjing Univ Posts & Telecommun, Jiangsu Synerget Innovat Ctr Adv Mat, Inst Adv Mat, Nanjing 210023, Jiangsu, Peoples R China
[3] State Key Lab Mol Engn Polymers, Shanghai 200433, Peoples R China
[4] Nanjing Tech Univ, Jiangsu Key Lab Flexible Elect, Nanjing 211816, Jiangsu, Peoples R China
[5] Nanjing Tech Univ, Synerget Innovat Ctr Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
来源：
PROGRESS IN CHEMISTRY | 2016年 / 28卷 / 10期
基金：
中国国家自然科学基金;
关键词：
water-soluble conjugated polymers; glycopolymer; fluorescence detection; lectin; LECTIN-BINDING; FLUORESCENT; OLIGOMER; POLYMER; POLY(ARYLENEETHYNYLENE)S; PREPOLYMERIZATION; POLYELECTROLYTES; NANOPARTICLES; POLYFLUORENE; BIOSENSOR;
D O I：
10.7536/PC160314
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Water-soluble conjugated polymers (WSCPs) have been applied to a wide range of fields such as chemical sensing, bio-sensing and bio-imaging. The advantages of WSCPs for these applications include their high brightness, good photo-stability, structure variety and sufficient solubility in aqueous solution. WSCPs are usually decorated with water-soluble ionic groups or polymers on their sides or end groups. Sugars are a kind of biomolecules existing naturally and most of them have the features of water-solubility, therefore in recent years researchers have introduced sugar compounds into conjugated polymers leading to water-soluble conjugated glycopolymers with the biological properties of carbonhydrates. In this review, we summarize the recent development in the synthesis of water-soluble conjugated glycopolymers and their applications in terms of lectin-sensing, bacteria-sensing and live-cell imaging. Finally, we point out the peculiarity, developing trend and the challenges of water-soluble conjugated glycopolymers.
引用
收藏
页码：1489 / 1500
页数：12
相关论文
共 55 条
[1]   Fluorescent Vesicles Consisting of Galactose-based Amphiphilic Copolymers with a π-Conjugated Sequence Self-assembled in Water [J].
Aissou, Karim ;
Pfaff, Andre ;
Giacomelli, Cristiano ;
Travelet, Christophe ;
Mueller, Axel H. E. ;
Borsali, Redouane .
MACROMOLECULAR RAPID COMMUNICATIONS, 2011, 32 (12) :912-916
[2]   Synthesis of poly(aryleneethynylene)s bearing glucose units as substituents [J].
Babudri, F ;
Colangiuli, D ;
Di Lorenzo, PA ;
Farinola, GM ;
Hassan Omar, O ;
Naso, F .
CHEMICAL COMMUNICATIONS, 2003, (01) :130-131
[3]  
Bark M G, 2000, BIOCONJUGATE CHEM, V11, P777
[4]   A 'litmus test' for molecular recognition using artificial membranes [J].
Charych, D ;
Cheng, Q ;
Reichert, A ;
Kuziemko, G ;
Stroh, M ;
Nagy, JO ;
Spevak, W ;
Stevens, RC .
CHEMISTRY & BIOLOGY, 1996, 3 (02) :113-120
[5]   Fluorous-based carbohydrate Quartz Crystal Microbalance [J].
Chen, Lei ;
Sun, Pengfei ;
Chen, Guosong .
CARBOHYDRATE RESEARCH, 2015, 405 :66-69
[6]   Glucosamine Hydrochloride Functionalized Water-Soluble Conjugated Polyfluorene: Synthesis, Characterization, and Interactions with DNA [J].
Chen, Oi ;
Cheng, Qian-Yi ;
Zhao, Yan-Chao ;
Han, Bao-Hang .
MACROMOLECULAR RAPID COMMUNICATIONS, 2009, 30 (19) :1651-1655
[7]   Water-soluble conjugated polyelectrolyte with pendant glycocluster: Synthesis and its interaction with heparin [J].
Chen, Qi ;
Cui, Yi ;
Cao, Jie ;
Han, Bao-Hang .
POLYMER, 2011, 52 (02) :383-390
[8]   Fluorescent Conjugated Polyfluorene with Pendant Lactopyranosyl Ligands for Studies of Ca2+-Mediated Carbohydrate-Carbohydrate Interaction [J].
Chen, Qi ;
Cui, Yi ;
Zhang, Tian-Long ;
Cao, Jie ;
Han, Bao-Hang .
BIOMACROMOLECULES, 2010, 11 (01) :13-19
[9]   Triphenylamine-based fluorescent conjugated glycopolymers: Synthesis, characterization and interactions with lectins [J].
Chen, Qi ;
Xu, Yonghua ;
Du, Yuguo ;
Han, Bao-Hang .
POLYMER, 2009, 50 (13) :2830-2835
[10]   Prepolymerization and Postpolymerization Functionalization Approaches to Fluorescent Conjugated Carbazole-Based Glycopolymers via "Click Chemistry" [J].
Chen, Qi ;
Han, Bao-Hang .
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2009, 47 (11) :2948-2957
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