Comparison of the Vidas C-difficile GDH Automated Enzyme-Linked Fluorescence Immunoassay (ELFA) with Another Commercial Enzyme Immunoassay (EIA) (Quik Chek-60), Two Selective Media, and a PCR Assay for gluD for Detection of Clostridium difficile in Fecal Samples

被引：18
作者：
Davies, K. A. [1 ]
Berry, C. E. [1 ]
Morris, K. A. [1 ]
Smith, R. [2 ]
Young, S. [2 ]
Davis, T. E. [3 ]
Fuller, D. D. [3 ]
Buckner, R. J. [3 ]
Wilcox, M. H. [1 ]
机构：
[1] Leeds Teaching Hosp Trust, Dept Microbiol, Leeds, W Yorkshire, England
[2] Tricore Reference Lab, Albuquerque, NM USA
[3] Indiana Univ, Dept Pathol & Lab Med, Indianapolis, IN 46204 USA
来源：
JOURNAL OF CLINICAL MICROBIOLOGY | 2015年 / 53卷 / 06期
关键词：
GLUTAMATE-DEHYDROGENASE; INFECTION; DIAGNOSIS; TOXIN;
D O I：
10.1128/JCM.00649-15
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Prevention and management of Clostridium difficile infection (CDI) can be improved by rapid and reliable diagnostics. The Vidas C. difficile glutamate dehydrogenase assay had performance comparable to that of the Quik Chek-60 assay (overall agreement, 95%) and a sensitivity of >93%; thus, it is suitable as the first test in two-stage algorithms for a CDI diagnosis.
引用
收藏
页码：1931 / 1934
页数：4
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