Treatment of Neonatal Asphyxia with a Special Focus on Therapeutic Hypothermia

被引：14

作者：

Flemmer, A. W. ^{[1
]}

Maier, R. F. ^{[2
]}

Hummler, H. ^{[3
]}

机构：

[1] Univ Munich, Neonatol Kinderklin, Perinatalzentrum, D-81377 Munich, Germany

[2] Univ Klinikum Giessen & Marbug, Klin Kinder & Jugendmed Marburg, Giessen, Germany

[3] Univ Ulm Klinikum, Sekt Neonatol & Padiatr Intens Med, Ulm, Germany

来源：

KLINISCHE PADIATRIE | 2014年 / 226卷 / 01期

关键词：

neonatal asphyxia; treatment; hypothermia; hypoxic ischemic encephalopathy; HYPOXIC-ISCHEMIC ENCEPHALOPATHY; WHOLE-BODY HYPOTHERMIA; SYSTEMIC HYPOTHERMIA; MODERATE HYPOTHERMIA; PERINATAL ASPHYXIA; TERM NEWBORNS; RESUSCITATION; OUTCOMES; INFANTS; AIR;

D O I：

10.1055/s-0033-1361104

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In recent years the treatment of newborns for neonatal asphyxia has experienced a lot of new developments. A major milestone were the positive results of various trials for prophylactic treatment of hypoxic-ischemic encephalopathy by moderate cooling of the child or of his head. With this paper we attempt to provide a consented guideline to aid in the treatment decision for affected newborns and thus achieve a more homogeneous treatment strategy throughout Germany.

引用

页码：29 / 37

页数：9

共 30 条

[11] A systematic review of the role of intrapartum hypoxia-ischemia in the causation of neonatal encephalopathy [J].

Graham, Ernest M. ;

Ruis, Kristy A. ;

Hartman, Adam L. ;

Northington, Frances J. ;

Fox, Harold E. .

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2008, 199 (06) :587-595

[12] Developmental Outcome at 6.5 Years After Acidosis in Term Newborns: A Population-Based Study [J].

Hafstrom, Maria ;

Ehnberg, Siv ;

Blad, Sofia ;

Noren, Hakan ;

Renman, Cecilia ;

Rosen, Karl Gustaf ;

Kjellmer, Ingemar .

PEDIATRICS, 2012, 129 (06) :E1501-E1507

[13] The prognostic value of early aEEG in asphyxiated infants undergoing systemic hypothermia treatment [J].

Hallberg, B. ;

Grossmann, K. ;

Bartocci, M. ;

Blennow, M. .

ACTA PAEDIATRICA, 2010, 99 (04) :531-536

[14] Cooling for newborns with hypoxic ischaemic encephalopathy [J].

Jacobs, Susan E. ;

Berg, Marie ;

Hunt, Rod ;

Tarnow-Mordi, William O. ;

Inder, Terrie E. ;

Davis, Peter G. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2013, (01)

[15] Whole-Body Hypothermia for Term and Near-Term Newborns With Hypoxic-Ischemic Encephalopathy A Randomized Controlled Trial [J].

Jacobs, Susan E. ;

Morley, Colin J. ;

Inder, Terrie E. ;

Stewart, Michael J. ;

Smith, Katherine R. ;

McNamara, Patrick J. ;

Wright, Ian M. R. ;

Kirpalani, Haresh M. ;

Darlow, Brian A. ;

Doyle, Lex W. .

ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE, 2011, 165 (08) :692-700

[16] Mild hypothermia via selective head cooling as neuroprotective therapy in term neonates with perinatal asphyxia: an experience from a single neonatal intensive care unit [J].

Lin, Z-L ;

Yu, H-M ;

Lin, J. ;

Chen, S-Q ;

Liang, Z-Q ;

Zhang, Z-Y .

JOURNAL OF PERINATOLOGY, 2006, 26 (03) :180-184

[17] Predicting motor outcome and death in term hypoxic-ischemic encephalopathy [J].

Martinez-Biarge, M. ;

Diez-Sebastian, J. ;

Kapellou, O. ;

Gindner, D. ;

Allsop, J. M. ;

Rutherford, M. A. ;

Cowan, F. M. .

NEUROLOGY, 2011, 76 (24) :2055-2061

[18]

Pappas A, 2011, J PEDIAT, P158

[19]

Perlman J M, 2010, INT CONSENSUS CARDIO, pe1319

[20] Room air resuscitation of the depressed newborn: A systematic review and meta-analysis [J].

Rabi, Yacov ;

Rabi, Doreen ;

Yee, Wendy .

RESUSCITATION, 2007, 72 (03) :353-363

← 1 2 3 →