Arylmethyl esters as protecting groups for carboxylic, carbonic and carbamic acids: deprotection via homogeneous palladium-catalyzed hydrogenolysis

被引：15

作者：

Boutros, A ^{[1
]}

Legros, JY ^{[1
]}

Fiaud, JC ^{[1
]}

机构：

[1] Univ Paris 11, CNRS, Lab Catalyse Mol, UPRESA 8075,Inst Chim Mol Orsay, F-91405 Orsay, France

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 41期

关键词：

catalysis; palladium; palladium compounds; protecting groups; quinolines;

D O I：

10.1016/S0040-4039(99)01457-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-Quinolylmethyl (4-QUI) esters of carboxylic acids and 1-naphthylmethyl (1-NAP) esters of carbonic and carbamic acids are reduced by palladium-catalyzed hydrogenolysis by formate anion. The reaction conditions are compatible with the presence of a benzyl ester and of an alkene double bond. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：7329 / 7332

页数：4

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