Chimeric Antigen Receptors With Distinct Signaling Domains Can Reprogram T Cells

被引：0
|
作者：
Kawalekar, Omkar U. [1 ]
O'Connor, Roddy S. [1 ]
Fraietta, Joseph [1 ]
Guedan, Sonia [1 ]
Scholler, John [1 ,2 ]
Milone, Michael C. [1 ]
June, Carl H. [1 ,2 ]
机构：
[1] Univ Penn, Pathol & Lab Med, Philadelphia, PA 19104 USA
[2] Univ Penn, Abramson Canc Ctr, Philadelphia, PA 19104 USA
来源：
MOLECULAR THERAPY | 2015年 / 23卷
关键词：
D O I：
10.1016/S1525-0016(16)34125-9
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
516
引用
收藏
页码：S206 / S207
页数：2
相关论文
共 50 条
  • [21] Grafting chimeric antigen receptors to redirect T cells Carving the CAR
    Riddell, S. R.
    Protzer, U.
    GENE THERAPY, 2010, 17 (10) : 1191 - 1192
  • [22] Chimeric Antigen Receptors Modified T-Cells for Cancer Therapy
    Dai, Hanren
    Wang, Yao
    Lu, Xuechun
    Han, Weidong
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2016, 108 (07):
  • [23] Genetic Modification of T Cells with Chimeric Antigen Receptors: A Laboratory Manual
    Golumba-Nagy, Viktoria
    Kuehle, Johannes
    Abken, Hinrich
    HUMAN GENE THERAPY METHODS, 2017, 28 (06) : 302 - 309
  • [24] A Direct Comparison of the In Vivo Efficacy and in Vitro Signaling of Chimeric Antigen Receptors and Endogenous T Cell Receptors
    Kohler, Mark Eric
    Yang, Yinmeng
    Sepulveda, Gian
    Fry, Terry J.
    BLOOD, 2017, 130
  • [25] Evaluation of Intracellular Signaling Downstream Chimeric Antigen Receptors
    Karlsson, Hannah
    Svensson, Emma
    Gigg, Camilla
    Jarvius, Malin
    Olsson-Stromberg, Ulla
    Savoldo, Barbara
    Dotti, Gianpietro
    Loskog, Angelica
    PLOS ONE, 2015, 10 (12):
  • [26] Genetic engineering of T cells with chimeric antigen receptors for hematological malignancy immunotherapy
    Dongdong Ti
    Yunfei Niu
    Zhiqiang Wu
    Xiaobing Fu
    Weidong Han
    Science China(Life Sciences), 2018, (11) : 1320 - 1332
  • [27] Genetic engineering of T cells with chimeric antigen receptors for hematological malignancy immunotherapy
    Dongdong Ti
    Yunfei Niu
    Zhiqiang Wu
    Xiaobing Fu
    Weidong Han
    Science China Life Sciences, 2018, 61 : 1320 - 1332
  • [28] Immunotherapy: T cells with chimeric antigen receptors, checkpoint inhibitors and bispecific antibodies
    Kerjean, Elodie
    HEMATOLOGIE, 2020, 26 (01): : 82 - 89
  • [29] Chimeric antigen receptors induce inflammatory program in human regulatory T cells
    Cochrane, Russell
    Robino, Rob
    Granger, Bryan
    Vaena, Silvia
    Romeo, Martin
    Allen, Eva
    Villella, Emily
    De Cubas, Aguirre
    Berto, Stefano
    Ferreira, Leonardo
    JOURNAL OF IMMUNOLOGY, 2024, 212 (01):
  • [30] Identification of Chimeric Antigen Receptors That Mediate Constitutive or Inducible Proliferation of T Cells
    Frigault, Matthew J.
    Lee, Jihyun
    Basil, Maria Ciocca
    Carpenito, Carmine
    Motohashi, Shinichiro
    Scholler, John
    Kawalekar, Omkar U.
    Guedan, Sonia
    McGettigan, Shannon E.
    Posey, Avery D., Jr.
    Ang, Sonny
    Cooper, Laurence J. N.
    Platt, Jesse M.
    Johnson, F. Brad
    Paulos, Chrystal M.
    Zhao, Yangbing
    Kalos, Michael
    Milone, Michael C.
    June, Carl H.
    CANCER IMMUNOLOGY RESEARCH, 2015, 3 (04) : 356 - U131
12345