A facile two-carbon ring expansion process based on the 2-cyano-1-vinylcycloalkanolsystem

被引：9

作者：

Shia, KS ^{[1
]}

Jan, NW

Zhu, JL

Ly, TW

Liu, HJ

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

[2] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 37期

基金：

加拿大自然科学与工程研究理事会;

关键词：

ring transformations; alcohols; cyano compounds; ketones;

D O I：

10.1016/S0040-4039(99)01401-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Upon exposure to potassium hydride in THF in the presence of 18-crown-6, several 2-cyano-1-vinylcycloalkanol derivatives were found to undergo ring enlargement to give the corresponding gamma-cyano cycloalkanones in synthetically useful yields. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：6753 / 6756

页数：4