Regulation of nucleosome dynamics by histone modifications

被引：632

作者：

Zentner, Gabriel E. ^{[1
]}

Henikoff, Steven ^{[1
,2
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Div Basic Sci, Seattle, WA 98104 USA

[2] Fred Hutchinson Canc Res Ctr, Howard Hughes Med Inst, Seattle, WA 98104 USA

来源：

NATURE STRUCTURAL & MOLECULAR BIOLOGY | 2013年 / 20卷 / 03期

基金：

美国国家卫生研究院;

关键词：

DNA-REPLICATION; H2B UBIQUITYLATION; CHROMATIN-STRUCTURE; SET2; METHYLATION; ADP-RIBOSYLATION; ACTIVE CHROMATIN; GENE ACTIVATION; H3; ACETYLATION; GENOME;

D O I：

10.1038/nsmb.2470

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chromatin is a dynamic structure that must respond to myriad stimuli to regulate access to DNA, and chemical modification of histones is a major means by which the cell modulates nucleosome mobility and turnover. Histone modifications are linked to essentially every cellular process requiring DNA access, including transcription, replication and repair. Here we consider properties of the major types of histone modification in the context of their associated biological processes to view them in light of the cellular mechanisms that regulate nucleosome dynamics.

引用

页码：259 / 266

页数：8

共 110 条

[1] Functional mammalian homologues of the Drosophila PEV-modifier Su(var)3-9 encode centromere-associated proteins which complex with the heterochromatin component M31 [J].

Aagaard, L ;

Laible, G ;

Selenko, P ;

Schmid, M ;

Dorn, R ;

Schotta, G ;

Kuhfittig, S ;

Wolf, A ;

Lebersorger, A ;

Singh, PB ;

Reuter, G ;

Jenuwein, T .

EMBO JOURNAL, 1999, 18 (07) :1923-1938

[2] ACETYLATION + METHYLATION OF HISTONES + THEIR POSSIBLE ROLE IN REGULATION OF RNA SYNTHESIS [J].

ALLFREY, VG ;

FAULKNER, R ;

MIRSKY, AE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1964, 51 (05) :786-+

[3] New nomenclature for chromatin-modifying enzymes [J].

Allis, C. David ;

Berger, Shelley L. ;

Cote, Jacques ;

Dent, Sharon ;

Jenuwien, Thomas ;

Kouzarides, Tony ;

Pillus, Lorraine ;

Reinberg, Danny ;

Shi, Yang ;

Shiekhattar, Ramin ;

Shilatifard, Ali ;

Workman, Jerry ;

Zhang, Yi .

CELL, 2007, 131 (04) :633-636

[4] Assembly and Functions of Heterochromatin in the Fission Yeast Genome [J].

Aygun, O. ;

Grewal, S. I. S. .

NUCLEAR ORGANIZATION AND FUNCTION, 2010, 75 :259-267

[5] A Peek into the Complex Realm of Histone Phosphorylation [J].

Banerjee, Taraswi ;

Chakravarti, Debabrata .

MOLECULAR AND CELLULAR BIOLOGY, 2011, 31 (24) :4858-4873

[6] Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain [J].

Bannister, AJ ;

Zegerman, P ;

Partridge, JF ;

Miska, EA ;

Thomas, JO ;

Allshire, RC ;

Kouzarides, T .

NATURE, 2001, 410 (6824) :120-124

[7] Fast signals and slow marks: the dynamics of histone modifications [J].

Barth, Teresa K. ;

Imhof, Axel .

TRENDS IN BIOCHEMICAL SCIENCES, 2010, 35 (11) :618-626

[8] Genome-wide function of H2B ubiquitylation in promoter and genic regions [J].

Batta, Kiran ;

Zhang, Zhenhai ;

Yen, Kuangyu ;

Goffman, David B. ;

Pugh, B. Franklin .

GENES & DEVELOPMENT, 2011, 25 (21) :2254-2265

[9] Protein Arginine Methylation in Mammals: Who, What, and Why [J].

Bedford, Mark T. ;

Clarke, Steven G. .

MOLECULAR CELL, 2009, 33 (01) :1-13

[10] DNA replication in eukaryotic cells [J].

Bell, SP ;

Dutta, A .

ANNUAL REVIEW OF BIOCHEMISTRY, 2002, 71 :333-374

← 1 2 3 4 5 6 7 8 9 10 →