A novel class of conformationally restricted oligonucleotide analogues: Synthesis of 2',3'-bridged monomers and RNA-selective hybridisation

被引：37
|
作者：
Nielsen, P
Pfundheller, HM
Wengel, J
机构：
[1] ODENSE UNIV,DEPT CHEM,DK-5230 ODENSE M,DENMARK
[2] UNIV COPENHAGEN,DEPT CHEM,DK-2100 COPENHAGEN,DENMARK
来源：
CHEMICAL COMMUNICATIONS | 1997年 / 09期
关键词：
D O I：
10.1039/a608231i
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel 2',3'-bicyclic nucleoside 5 has been synthesised and incorporated into oligonucleotide analogues resulting in strong and selective binding to an RNA complement.
引用
收藏
页码：825 / 826
页数：2
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