Conversion of homochiral amines and α-amino esters to their chiral 1,2,3,5-substituted pyrrole derivatives via gold-catalysed amination/annulation reactions of 2-propynyl-1,3-dicarbonyl compounds

被引：67
作者：
Arcadi, A
Di Giuseppe, S
Marinelli, F
Rossi, E
机构：
[1] Fac Sci, Dipartimento Chim Ingn Chim & Mat, I-67100 Laquila, Italy
[2] Univ Milan, Fac Farm, Ist Chim Organ, I-20133 Milan, Italy
来源：
TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 19期
关键词：
D O I：
10.1016/S0957-4166(01)00468-2
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Homochiral primary amines, amino alcohols and alpha -amino esters have been reacted with 2-propynyl-1,3-dicarbonyl compounds under gold catalysis leading to 1,2,5-trisubstituted 3-acylpyrrole derivatives in moderate to high yields and high enantiomeric excess. (C) 2001 Elsevier Science Ltd. All rights reserved.
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页码：2715 / 2720
页数：6
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