HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women

被引：6
作者：
Mane, Arati [1 ]
Kulkarni, Smita [1 ]
Ghate, Manisha [1 ]
Risbud, Arun [1 ]
Thakar, Madhuri [1 ]
机构：
[1] Natl AIDS Res Inst, MIDC, Pune 411026, Maharashtra, India
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2013年 / 75卷 / 01期
关键词：
HIV-1; Genital shedding; Lactobacilli; IMMUNODEFICIENCY-VIRUS TYPE-1; BACTERIAL VAGINOSIS;
D O I：
10.1016/j.diagmicrobio.2012.09.009
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load (r(2) = - 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码：112 / 114
页数：3
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