HIV-1 RNA shedding in the female genital tract is associated with reduced quantity of Lactobacilli in clinically asymptomatic HIV-positive women

被引：6

作者：

Mane, Arati ^{[1
]}

Kulkarni, Smita ^{[1
]}

Ghate, Manisha ^{[1
]}

Risbud, Arun ^{[1
]}

Thakar, Madhuri ^{[1
]}

机构：

[1] Natl AIDS Res Inst, MIDC, Pune 411026, Maharashtra, India

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2013年 / 75卷 / 01期

关键词：

HIV-1; Genital shedding; Lactobacilli; IMMUNODEFICIENCY-VIRUS TYPE-1; BACTERIAL VAGINOSIS;

D O I：

10.1016/j.diagmicrobio.2012.09.009

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We quantified vaginal lactobacilli and determined their relationship with genital HIV-1 shedding and found a significant negative association between reduced quantity of lactobacilli and cervical HIV-1 viral load (r(2) = - 0.8900, P < 0.01), which may have implications of increased chances of sexual transmission of HIV-1 and genital infections. (C) 2013 Elsevier Inc. All rights reserved.

引用

页码：112 / 114

页数：3

共 39 条

[21] Lower levels of HIV-2 than HIV-1 in the female genital tract: correlates and longitudinal assessment of viral
Hawes, Stephen E.
Sow, Papa Salif
Stern, Joshua E.
Critchlow, Cathy W.
Gottlieb, Geoffrey S.
Kiviat, Nancy B.
AIDS, 2008, 22 (18) : 2517 - 2525
[22] The effects of antiretroviral therapy on HIV-1 RNA loads in seminal plasma in HIV-positive patients with and without urethritis
Sadiq, ST
Taylor, S
Kaye, S
Bennett, J
Johnstone, R
Byrne, P
Copas, AJ
Drake, SM
Pillay, D
Weller, I
AIDS, 2002, 16 (02) : 219 - 225
[23] HIV-1 DNA shedding in genital ulcers and its associated risk factors in Pune, India
Gadkari, DA
Quinn, TC
Gangakhedkar, RR
Mehendale, SM
Divekar, AD
Risbud, AR
Chan-Tack, K
Shepherd, M
Gaydos, C
Bollinger, RC
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, 1998, 18 (03) : 277 - 281
[24] Induction of Innate Immune Responses in the Female Genital Tract: Friend or Foe of HIV-1 Infection?
Mian, M. Firoz
Ashkar, Ali A.
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[25] Interval female sterilization of HIV-1 positive women: Laparoscopy versus minilaparotomy
Taneepanichskul, S
Intaraprasert, S
Chaturachinda, K
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[26] Hormonal influence on HIV-1 transmission in the female genital tract: New insights from systems biology
Dupont, Haley A.
Lam, Jeff
Woods, Matthew W.
Zahoor, Mohammed A.
Kaushic, Charu
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[27] High Level of Soluble HLA-G in the Female Genital Tract of Beninese Commercial Sex Workers Is Associated with HIV-1 Infection
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Lajoie, Julie
Labbe, Annie-Claude
Zannou, Marcel D.
Fowke, Keith R.
Alary, Michel
Poudrier, Johanne
Roger, Michel
PLOS ONE, 2011, 6 (09):
[28] HIV Shedding in the Female Genital Tract of Women on ART and Progestin Contraception: Extended Follow-up Results of a Randomized Clinical Trial
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Hurst, Stacey
Nelson, Julie A. E.
Cottrell, Mackenzie L.
Corbett, Amanda
Chinula, Lameck
Msika, Albans
Haddad, Lisa B.
Tang, Jennifer H.
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Shukre, Subodh
Bichare, Shubhangi
Kadam, Poonam
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Paranjape, Ramesh
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[30] Decrease in Seminal HIV-1 RNA Load After Praziquantel Treatment of Urogenital Schistosomiasis Coinfection in HIV-Positive Men-An Observational Study
Midzi, Nicholas
Mduluza, Takafira
Mudenge, Boniface
Foldager, Leslie
Leutscher, Peter D. C.
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