At present, four components of public health-human capital, economy, infrastructure and modern technologies-are priorities. The prospects of financial and economic development of the national economy are connected with the digital economy. It is predicted that the digital economy will change the format of existing economic relations and business models in economics. Health care digitalization is inextricably related to the economic development of the country and with all sectors of the economy. The objective of the digital economy program, aimed at improving the lives of Russians by improving the quality of goods and services produced using the latest digital technologies, is fully related to the health sector. The article considers healthcare digitalization as a complex research of positive and negative factors that can affect the quality of medical services, the performance of the state guarantees program of medical care, and ultimately, the quality of life of citizens and the implementation of the state strategic plans as a whole. The authors give examples confirming that the health care digitalization is successfully implemented in the regions of the Russian Federation, and make appropriate generalizations and conclusions.