Active immunisation against human tick-borne diseases

被引：3

作者：

Bratu, S ^{[1
]}

Lutwick, LI

机构：

[1] Suny Downstate Med Ctr, Brooklyn, NY 11203 USA

[2] VA NY Harbor Healthcare Syst, Brooklyn, NY 11209 USA

来源：

EXPERT OPINION ON BIOLOGICAL THERAPY | 2002年 / 2卷 / 02期

关键词：

immunisations; Lyme disease; ticks; vaccines;

D O I：

10.1517/14712598.2.2.187

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

With the development and licensure of a recombinant vaccine for the tickborne infection Lyme disease, more attention has been paid to other vaccines that have been used or are being developed for the prevention of other tickborne infections. This review highlights vaccine information for Lyme borreliosis, tick-borne encephalitis (TBE), Rocky Mountain spotted fever, tularaemia, Query (Q) fever, Kyasanur Forest disease (KFD) and tick paralysis. Additionally, discussion on the use of immunisation against the tick itself is included which not only can decrease veterinary tick burdens but may also decrease the transmission of arthropod-transmitted diseases.

引用

页码：187 / 195

页数：9

共 62 条

[1] The immunoglobulin (IgG) antibody response to OspA and OspB correlates with severe and prolonged Lyme arthritis and the IgG response to P35 correlates with mild and brief arthritis [J].