Colorimetric Detection of Creatinine Based on Plasmonic Nanoparticles via Synergistic Coordination Chemistry

被引:61
作者
Du, Jianjun [1 ]
Zhu, Bowen [2 ]
Leow, Wan Ru [2 ]
Chen, Shi [3 ]
Sum, Tze Chien [3 ]
Peng, Xiaojun [1 ]
Chen, Xiaodong [2 ]
机构
[1] Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
[2] Nanyang Technol Univ, Sch Mat Sci & Engn, Singapore 639798, Singapore
[3] Nanyang Technol Univ, Sch Phys & Math Sci, Div Phys & Appl Phys, Singapore 637371, Singapore
基金
新加坡国家研究基金会;
关键词
GOLD NANOPARTICLES; CAPILLARY-ELECTROPHORESIS; ELECTROCHEMICAL SENSOR; ARRAYS; URINE; SERUM; ASSAY; IONS;
D O I
10.1002/smll.201403369
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A simple and portable colorimetric assay for creatinine detection is fabricated based on the synergistic coordination of creatinine and uric acid with Hg2+ on the surface of gold nanoparticles, which exhibits good selectivity and sensitivity. Point-of-care clinical creatinine monitoring can be supported for monitoring renal function and diagnosing corresponding renal diseases at home. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:4104 / 4110
页数:7
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