Hair cortisol level as a retrospective marker of hypothalamic-pituitary-adrenal axis activity in horse foals

被引：50

作者：

Comin, Antonella ^{[2
]}

Veronesi, Maria C. ^{[1
]}

Montillo, Marta ^{[2
]}

Faustini, Massimo ^{[3
]}

Valentini, Silvia ^{[4
]}

Cairoli, Fausto ^{[1
]}

Prandi, Alberto ^{[2
]}

机构：

[1] Univ Milan, Dept Vet Clin Sci, Milan, Italy

[2] Univ Udine, Dept Food Sci, I-33100 Udine, Italy

[3] Univ Milan, Dept Vet Sci & Technol Food Safety, Milan, Italy

[4] Allevamento Toniatti, S Michele Al Tagliamento, VE, Italy

来源：

VETERINARY JOURNAL | 2012年 / 194卷 / 01期

关键词：

Horse; Foal; Hair; Cortisol; HPA axis;

D O I：

10.1016/j.tvjl.2012.04.006

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Stimulation of the hypothalamic-pituitary-adrenal (HPA) axis and elevated cortisol concentrations in fetal plasma are associated with foal maturity, viability and adaptation to independent life. However, non-invasive measurement of cortisol in hair samples has not yet been validated in horses. The current study developed a radioimmunoassay to analyse cortisol in horse hair and was used to measure cortisol hair concentration at birth and at 30 and 60 days of age as a retrospective study of HPA axis activity. Cortisol was detectable in the hair of foals from birth until 2 months, but decreased with time and varied greatly between individuals. Analysis of hair cortisol could be useful for non-invasive retrospective studies of HPA axis activity in perinatal horse. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：131 / 132

页数：2

共 7 条

[1] Cortisol determination in hair and faeces from domestic cats and dogs [J].