Broken hearts: Iron overload, ferroptosis and cardiomyopathy

被引：65

作者：

Conrad, Marcus ^{[1
]}

Proneth, Bettina ^{[1
]}

机构：

[1] Helmholtz Zentrum Munchen, Inst Dev Genet, Ingolstadter Landstr 1, D-85764 Neuherberg, Germany

来源：

CELL RESEARCH | 2019年 / 29卷 / 04期

关键词：

CELL-DEATH;

D O I：

10.1038/s41422-019-0150-y

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In a recently published paper in Proc Natl Acad Sci USA, Fang et al. elegantly demonstrated that doxorubicin treatment or transient ischemia/reperfusion in mice triggers ferroptosis, a distinctive form of necrotic cell death marked by irondependent lipid peroxidation, which is the main underlying mechanism in the pathogenesis of cardiomyopathy.

引用

页码：263 / 264

页数：2

共 12 条

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