Comparison of detection and quantification of HBV DNA in chronic HBeAg negative and positive patients by Abbott RealTime HBV and Roche Cobas TaqMan HBV assays

被引:12
|
作者
Morris, Carol J. [1 ]
Hill, Mary [1 ]
de Medina, Maria [1 ]
Herman, Christine [2 ]
Cloherty, Gavin A. [2 ]
Martin, Paul [1 ]
机构
[1] Univ Miami, Leonard M Miller Sch Med, Miami, FL USA
[2] Abbott Mol, Des Plaines, IL USA
关键词
HBV viral load; HBeAg negative; HBeAg positive; Abbott RealTime HBV assay; Cobas TaqMan HBV assay; B-VIRUS DNA; CHRONIC HEPATITIS-B; TIME PCR ASSAY; PERFORMANCE; LEVEL; RISK;
D O I
10.1016/j.jviromet.2013.06.036
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Monitoring the serum hepatitis B viral DNA levels with sensitive realtime PCR assays is strongly recommended for the management of patients with chronic HBV infection. This study compares the performance of two realtime HBV quantitative PCR assays with samples from chronic HBeAg(+) and HBeAg(-) patients. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码:391 / 393
页数:3
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