Gadolinium-based contrast agents review of recent literature on magnetic resonance imaging signal intensity changes and tissue deposits, with emphasis on pediatric patients

被引：49
|
作者：
Blumfield, Einat [1 ]
Swenson, David W. [2 ]
Iyer, Ramesh S. [3 ]
Stanescu, A. Luana [3 ]
机构：
[1] Childrens Hosp Montefiore, Albert Einstein Coll Med, Dept Radiol, 111E 210th St, Bronx, NY 10461 USA
[2] Brown Univ, Alpert Med Sch, Dept Diagnost Imaging, Rhode Isl Hosp,Hasbro Childrens Hosp, Providence, RI USA
[3] Univ Washington, Sch Med, Dept Radiol, Seattle Childrens Hosp, Seattle, WA 98195 USA
来源：
PEDIATRIC RADIOLOGY | 2019年 / 49卷 / 04期
关键词：
Brain; Children; Deposition; Gadolinium; Gadolinium-based contrast agents; Magnetic resonance imaging; T1; signal; UNENHANCED T1-WEIGHTED IMAGES; NEPHROGENIC SYSTEMIC FIBROSIS; HUMAN BONE TISSUE; DENTATE NUCLEUS; GLOBUS-PALLIDUS; MR-IMAGES; GADOBENATE DIMEGLUMINE; MULTIPLE ADMINISTRATIONS; PROGRESSIVE INCREASE; GD-DTPA;
D O I：
10.1007/s00247-018-4304-8
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
Gadolinium has been used as a base for contrast agents in MRI for the last three decades. Numerous studies over the last 4years have reported increased signal intensity in deep brain nuclei in non-contrast MRI images following gadolinium-based contrast agent (GBCA) administration. Pathology studies performed on adults and children, and rodent necropsy studies have also shown gadolinium deposition in brain and other tissues after GBCA administration. The purpose of this review was to summarize and discuss the knowledge gained from these reports and the relevance for imaging pediatric patients.
引用
收藏
页码：448 / 457
页数：10
相关论文
共 50 条
  • [41] Gadolinium-Based Contrast Agents in Pregnant Women: A Literature Review of MRI Safety
    Alghamdi Sr, Sami A.
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (05)
  • [42] Evaluation of the Effect of Multiple Linear Gadolinium-Based Contrast Agent Exposures on the Signal Intensity of the Dentate Nucleus in Multiple Sclerosis Patients
    Mohammadzadeh, Maryam
    Sheibani, Zahra
    Shakiba, Madjid
    Azimi, Amir Reza
    Hashemzadeh, Arezou
    Barzegar, Mojtaba
    Naghibi, Hamed
    IRANIAN JOURNAL OF RADIOLOGY, 2021, 18 (04)
  • [43] Risks and Options With Gadolinium-Based Contrast Agents in Patients With CKD: A Review
    Rudnick, Michael R.
    Wahba, Ihab M.
    Leonberg-Yoo, Amanda K.
    Miskulin, Dana
    Litt, Harold, I
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2021, 77 (04) : 517 - 528
  • [44] Functional Magnetic Resonance Imaging of the Kidneys-With and Without Gadolinium-Based Contrast
    Zhang, Jeff L.
    ADVANCES IN CHRONIC KIDNEY DISEASE, 2017, 24 (03) : 162 - 168
  • [45] Rapid deterioration of renal insufficiency after magnetic resonance imaging with gadolinium-based contrast agent
    Fujisaki, K.
    Ono-Fujisaki, A.
    Kura-Nakamura, N.
    Komune, N.
    Hirakawa, N.
    Tsuruya, K.
    Komune, S.
    Iida, M.
    CLINICAL NEPHROLOGY, 2011, 75 (03) : 251 - 254
  • [46] Incidence of Nephrogenic Systemic Fibrosis in Patients Undergoing Dialysis After Contrast-Enhanced Magnetic Resonance Imaging With Gadolinium-Based Contrast Agents The Prospective Fibrose Nephrogenique Systemique Study
    Amet, Sabine
    Launay-Vacher, Vincent
    Clement, Olivier
    Frances, Camille
    Tricotel, Aurore
    Stengel, Benedicte
    Gauvrit, Jean-Yves
    Grenier, Nicolas
    Reinhardt, Genevieve
    Janus, Nicolas
    Choukroun, Gabriel
    Laville, Maurice
    Deray, Gilbert
    INVESTIGATIVE RADIOLOGY, 2014, 49 (02) : 109 - 115
  • [47] Imaging of pediatric head and neck rhabdomyosarcomas with emphasis on magnetic resonance imaging and a review of the literature
    Yang, WT
    Kwan, WH
    Li, CK
    Metreweli, C
    PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1997, 14 (03) : 243 - 257
  • [48] Pediatric Brain: Repeated Exposure to Linear Gadolinium-based Contrast Material Is Associated with Increased Signal Intensity at Unenhanced T1-weighted MR Imaging
    Flood, Thomas F.
    Stence, Nicholas V.
    Maloney, John A.
    Mirsky, David M.
    RADIOLOGY, 2017, 282 (01) : 222 - 228
  • [49] Diagnostic accuracy of non-contrast magnetic resonance enterography in detecting active bowel inflammation in pediatric patients with diagnosed or suspected inflammatory bowel disease to determine necessity of gadolinium-based contrast agents
    Kim, Stacy J.
    Ratchford, Thomas L.
    Buchanan, Paula M.
    Patel, Dhiren R.
    Tao, Ting Y.
    Teckman, Jeffrey H.
    Brown, Jeffrey J.
    Farmakis, Shannon G.
    PEDIATRIC RADIOLOGY, 2019, 49 (06) : 759 - 769
  • [50] Subsequent MRI of pediatric patients after an adverse reaction to Gadolinium-based contrast agents
    Hojreh, Azadeh
    Peyrl, Andreas
    Bundalo, Aleksandra
    Szepfalusi, Zsolt
    PLOS ONE, 2020, 15 (04):
12345