Case Study: Expedited development of a cation exchange polishing step for therapeutic monoclonal antibody purification using a miniaturized high-throughput approach

被引：0
|
作者：
Pan, Xiaoyu [1 ]
Surendar, Deepa [2 ]
Chang, Yu-Hsi [2 ]
Zolyomi, Ryan [2 ]
Tjandra, Hendri [2 ]
Hesslein, Ashley [3 ]
机构：
[1] Bayer, Berkeley, CA USA
[2] Bayer, Biol Dev, Union City, CA USA
[3] Bayer HealthCare, Berkeley, CA USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2017年 / 253卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
457-BIOT
引用
收藏
页数：1
相关论文
共 26 条
  • [1] Rapid development of cation exchange chromatography step elution for monoclonal antibody purification
    Young, Lucian
    Cai, Katherine
    Varma, Amit
    Huang, Ping Y.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [2] Case study: Model-based chromatography characterization for a monoclonal antibody cation exchange step
    Hunt, Steve
    Larsen, Trent
    Tolley, Kevin
    Belval, Tom
    Todd, Robert
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2014, 247
  • [3] Comparison of antibody purification conditions for anion-exchange resins using high-throughput screening
    Fuller, Shirin
    Hung, Bao-Shin
    Lovato-Tse, Martha
    McDonald, Paul
    Lebreton, Benedicte
    St John, Rick
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 241
  • [4] Development of intermediate purification step in insulin process using a high throughput approach
    Heldin, Eva
    Hallgren, Elisabeth
    Shanagar, Jamil
    Gronlund, Sara
    Eriksson, Kjell
    Tunes, Heloisa
    Xavier, Mariza
    Vilela, Luciano
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 245
  • [5] High-Throughput Screening for the Development of a Monoclonal Antibody Affinity Precipitation Step Using ELP-Z Stimuli Responsive Biopolymers
    Sheth, Rahul D.
    Madan, Bhawna
    Chen, Wilfred
    Cramer, Steven M.
    BIOTECHNOLOGY AND BIOENGINEERING, 2013, 110 (10) : 2664 - 2676
  • [6] Purification of a monoclonal antibody using a novel high-capacity multimodal cation exchange nonwoven membrane
    Fan, Jinxin
    Sripada, Sobhana A.
    Pham, Dan N.
    Linova, Marina Y.
    Woodley, John M.
    Menegatti, Stefano
    Boi, Cristiana
    Carbonell, Ruben G.
    SEPARATION AND PURIFICATION TECHNOLOGY, 2023, 317
  • [7] PROCESS DEVELOPMENT FOR ROBUST REMOVAL OF AGGREGATES USING CATION EXCHANGE CHROMATOGRAPHY IN MONOCLONAL ANTIBODY PURIFICATION WITH IMPLEMENTATION OF QUALITY BY DESIGN
    Xu, Zhihao
    Li, Jason
    Zhou, Joe X.
    PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, 2012, 42 (02): : 183 - 202
  • [8] Use of high-throughput process development (HTPD) methods to develop a toxicology process: Cation and anion-exchange chromatography development case study
    Bill, Amber
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 255
  • [9] A practical strategy for using miniature chromatography columns in a standardized high-throughput workflow for purification development of monoclonal antibodies
    Welsh, John P.
    Petroff, Matthew G.
    Rowicki, Patricia
    Bao, Haiying
    Linden, Thomas
    Roush, David J.
    Pollard, Jennifer M.
    BIOTECHNOLOGY PROGRESS, 2014, 30 (03) : 626 - 635
  • [10] Study of Polymer Nanofilms Using for High-Throughput Screening in the Development of Transdermal Therapeutic System
    Suzuki, Takahiro
    Sato, Kanae
    Seki, Tomohiro
    Seki, Toshinobu
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2022, 70 (12) : 868 - 875
123