Cutaneous leukocyfoclastic vasculitis in a child with interleukin-12 receptor beta-1 deficiency

被引:19
作者
Kutukculer, N [1 ]
Genel, F
Aksu, G
Karapinar, B
Ozturk, C
Cavusoglu, C
Casanova, JL
Fieschi, C
机构
[1] Ege Univ, Fac Med, Dept Pediat, TR-35100 Izmir, Turkey
[2] Ege Univ, Fac Med, Dept Microbiol & Clin Microbiol, TR-35100 Izmir, Turkey
[3] Necker Med Sch, Lab Human Genet & Infect Dis, Pediat Immunol & Hematol Unit, Paris, France
关键词
D O I
10.1016/j.jpeds.2005.10.003
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
We report a patient with complete interleukin-12 receptor beta-1 deficiency associated with cutaneous leukocytoclastic vasculitis. The patient experienced Bacille Calmette Guerin, Mycobacterium chelonae, and Salmonella enteritidis infection. Vasculitis affecting both small arteries and postcapillary venules due to deposition of immune complexes was probably caused by S. enteritidis and/or M chelonae infection.
引用
收藏
页码:407 / 409
页数:3
相关论文
共 15 条
[1]   Mycobacterium fortuitum-chelonae complex infection in a child with complete interleukin-12 receptor beta 1 deficiency [J].
Aksu, G ;
Tirpan, C ;
Cavusoglu, C ;
Soydan, S ;
Altare, F ;
Casanova, JL ;
Kutukculer, N .
PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2001, 20 (05) :551-553
[2]   Impairment of mycobacterial immunity in human interleukin-12 receptor deficiency [J].
Altare, F ;
Durandy, A ;
Lammas, D ;
Emile, JF ;
Lamhamedi, S ;
Le Deist, F ;
Drysdale, P ;
Jouanguy, E ;
Döffinger, R ;
Bernaudin, F ;
Jeppsson, O ;
Gollob, JA ;
Meinl, E ;
Segal, AW ;
Fischer, A ;
Kumararatne, D ;
Casanova, JL .
SCIENCE, 1998, 280 (5368) :1432-1435
[3]   Genetic dissection of immunity to mycobacteria: The human model [J].
Casanova, JL ;
Abel, L .
ANNUAL REVIEW OF IMMUNOLOGY, 2002, 20 :581-620
[4]   Risk factors for endovascular infection due to nontyphoid salmonellae [J].
Chiu, CH ;
Ou, JT .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (07) :835-836
[5]  
de Jong R, 1998, SCIENCE, V280, P1435
[6]   Interferon-γ and interleukin-12 pathway defects and human disease [J].
Dorman, SE ;
Holland, SM .
CYTOKINE & GROWTH FACTOR REVIEWS, 2000, 11 (04) :321-333
[7]   The role of interleukin-12 in human infectious diseases: only a faint signature [J].
Fieschi, C ;
Casanova, JL .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2003, 33 (06) :1461-1464
[8]   Low penetrance, broad resistance, and favorable outcome of interleukin 12 receptor β1 deficiency:: Medical and immunological implications [J].
Fieschi, C ;
Dupuis, S ;
Catherinot, E ;
Feinberg, J ;
Bustamante, J ;
Breiman, A ;
Altare, F ;
Baretto, R ;
Le Deist, F ;
Kayal, S ;
Koch, H ;
Richter, D ;
Brezina, M ;
Aksu, G ;
Wood, P ;
Al-Jumaah, S ;
Raspall, M ;
Duarte, AJD ;
Tuerlinckx, D ;
Virelizier, JL ;
Fischer, A ;
Enright, A ;
Bernhöft, J ;
Cleary, AM ;
Vermylen, C ;
Rodriguez-Gallego, C ;
Davies, G ;
Blütters-Sawatzki, R ;
Siegrist, CA ;
Ehlayel, MS ;
Novelli, V ;
Haas, WH ;
Levy, J ;
Freihorst, J ;
Al-Hajar, S ;
Nadal, D ;
Vasconcelos, DD ;
Jeppsson, O ;
Kutukculer, N ;
Frecerova, K ;
Caragol, I ;
Lammas, D ;
Kumararatne, DS ;
Abel, L ;
Casanova, JL .
JOURNAL OF EXPERIMENTAL MEDICINE, 2003, 197 (04) :527-535
[9]   CASE-REPORT - SALMONELLOSIS COMPLICATED BY LEUKOCYTOCLASTIC VASCULITIS [J].
FINCHER, RME ;
THREADGILL, ST ;
CRANFORD, MS ;
WEBSTER, JS ;
HANLY, MG .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1991, 302 (05) :296-297
[10]   Risk factors for primary bacteremia and endovascular infection in patients without acquired immunodeficiency syndrome who have nontyphoid salmonellosis [J].
Hsu, RB ;
Tsay, YG ;
Chen, RJ ;
Chu, SH .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (07) :829-834