Thermal characterization of chitosan-grafted membranes to be used as wound dressings

被引:19
作者
Ferreira, P.
Coelho, J. F. J.
dos Santos, K. S. C. R.
Ferreira, E. I.
Gil, M. H.
机构
[1] Univ Coimbra, Fac Ciencias & Tecnol, Dept Engn Quim, P-3030290 Coimbra, Portugal
[2] Univ Sao Paulo, Fac Ciencias Farmaceut, Sao Paulo, Brazil
关键词
graft copolymerization; chitosan; wound healing;
D O I
10.1080/07328300600734085
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The graft copolymerization of the vinyl monomers onto chitosan was confirmed by FTIR and DMTA. The chitosan used was also characterized by DMTA, which allowed addressing some questions related to the typical thermal transitions of this biopolymer. The swelling capacity of the membranes was also determined. The chitosan-graft-AA-graft-HEMA with an equimolar ratio of HEMA and AA kept good swelling capacity without compromising its physical stability, which suggests it to be the best matrix for drug delivery systems.
引用
收藏
页码:233 / 251
页数:19
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