Discovery of a Novel Dihydroorotate Dehydrogenase Inhibitor That Induces Differentiation and Overcomes Ara-C Resistance of Acute Myeloid Leukemia Cells

被引：0

作者：

Kitazawa, Satoshi ^{[1
]}

Ishii, Yukiko ^{[1
]}

Makita-Suzuki, Keiko ^{[1
]}

Saito, Koichi ^{[1
]}

Takayanagi, Kensuke ^{[1
]}

Sugihara, Hiromi ^{[1
]}

Matsuda, Shun ^{[2
]}

Yamakawa, Takayuki ^{[1
]}

Tsutsui, Yasuhiro ^{[1
]}

Tanaka, Tadashi ^{[1
]}

Hatta, Tomohisa ^{[3
]}

Natsume, Tohru ^{[3
]}

Kondo, Toru ^{[4
]}

Ishikawa, Yuichi ^{[5
]}

Hagiwara, Shinji ^{[1
]}

Kiyoi, Hitoshi ^{[5
]}

机构：

[1] FUJIFILM Corp, Bio Sci & Engn Lab, Kaisei, Japan

[2] FUJIFILM Corp, Anal Technol Ctr, Minamiashigara, Japan

[3] Natl Inst Adv Ind Sci & Technol, Mol Profiling Res Ctr Drug Discovery, Tokyo, Japan

[4] Hokkaido Univ, Inst Med Genet, Div Stem Cell Biol, Sapporo, Hokkaido, Japan

[5] Nagoya Univ, Dept Hematol & Oncol, Grad Sch Med, Nagoya, Aichi, Japan

来源：

关键词：

D O I：

10.1182/blood-2019-121869

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

2663

引用

页数：4