Drug-induced valvular heart disease: An update

被引：33

作者：

Andrejak, Michel ^{[1
,2
]}

Tribouilloy, Christophe ^{[2
,3
]}

机构：

[1] CHU Amiens, Hop Sud, Serv Pharmacol Clin, F-80054 Amiens 1, France

[2] INSERM, U1088, Amiens, France

[3] CHU Amiens, Serv Cardiol, Amiens, France

来源：

ARCHIVES OF CARDIOVASCULAR DISEASES | 2013年 / 106卷 / 05期

关键词：

Drug induced valvular disease; Ergot alkaloids; Ergot-derived dopamine agonists; Norfenfluramine; Valvular regurgitation; APPETITE-SUPPRESSANT DRUGS; CARDIAC-VALVE REGURGITATION; PARKINSONS-DISEASE; BENFLUOREX THERAPY; DOPAMINE AGONISTS; TRICUSPID REGURGITATION; METHYSERGIDE THERAPY; INDUCED VALVULOPATHY; DIABETES-MELLITUS; FENFLURAMINE;

D O I：

10.1016/j.acvd.2013.02.003

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Numerous reports have shown an unquestionable association between fibrotic valve disease and the following drugs: ergot alkaloids (such as methysergide and ergotamine), ergot-derived dopaminergic agonists (such as pergolide and cabergoline) and drugs metabolized into norfenfluramine (such as fenfluramine, dexfenfluramine and benfluorex). This review focuses on different aspects of drug-induced valvular heart disease: historical background; echocardiographic features; different drugs recognized as being responsible for valvular heart disease; and pathophysiology. (C) 2013 Elsevier Masson SAS. All rights reserved.

引用

页码：333 / 339

页数：7

共 43 条

[31] VaIvular heart disease in patients taking pergolide [J].

Pritchett, AM ;

Morrison, JF ;

Edwards, WD ;

Schaff, HV ;

Connolly, HM ;

Espinosa, RE .

MAYO CLINIC PROCEEDINGS, 2002, 77 (12) :1280-1286

[32]

Ribera JR, 2003, REV ESP CARDIOL, V56, P215

[33]

Rothman RB, 2000, CIRCULATION, V102, P2836

[34] Effect of fenfluramine-derivative diet pills on cardiac valves: A meta-analysis of observational studies [J].

Sachdev, M ;

Miller, WC ;

Ryan, T ;

Jolis, JG .

AMERICAN HEART JOURNAL, 2002, 144 (06) :1065-1073

[35] Dopamine agonists and the risk of cardiac-valve regurgitation [J].

Schade, Rene ;

Andersohn, Frank ;

Suissa, Samy ;

Haverkamp, Wilhelm ;

Garbe, Edeltraut .

NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (01) :29-38

[36] Prevalence and determinants of valvulopathy in patients treated with dexfenfluramine [J].

Shively, BK ;

Roldan, CA ;

Gill, EA ;

Najarian, T ;

Loar, SB .

CIRCULATION, 1999, 100 (21) :2161-2167

[37] Increased Risk of Left Heart Valve Regurgitation Associated With Benfluorex Use in Patients With Diabetes Mellitus A Multicenter Study [J].

Tribouilloy, Christophe ;

Rusinaru, Dan ;

Marechaux, Sylvestre ;

Jeu, Antoine ;

Ederhy, Stephane ;

Donal, Erwan ;

Reant, Patricia ;

Arnalsteen, Elise ;

Boulanger, Jacques ;

Ennezat, Pierre-Vladimir ;

Garban, Thierry ;

Jobic, Yannick .

CIRCULATION, 2012, 126 (24) :2852-+

[38] Restrictive organic mitral regurgitation associated with benfluorex therapy [J].

Tribouilloy, Christophe ;

Rusinaru, Dan ;

Henon, Pierre ;

Tribouilloy, Laurence ;

Leleu, Francois ;

Andrejak, Michel ;

Sevestre, Henri ;

Peltier, Marcel ;

Caus, Thierry .

EUROPEAN JOURNAL OF ECHOCARDIOGRAPHY, 2010, 11 (07) :614-621

[39] Potential Cardiac Valve Effects of Dopamine Agonists in Hyperprolactinemia [J].

Valassi, Elena ;

Klibanski, Anne ;

Biller, Beverly M. K. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2010, 95 (03) :1025-1033

[40]

Vallette Sophie, 2010, Expert Rev Cardiovasc Ther, V8, P49, DOI 10.1586/erc.09.167

← 1 2 3 4 5 →