Drug-induced valvular heart disease: An update

被引：33
作者：
Andrejak, Michel [1 ,2 ]
Tribouilloy, Christophe [2 ,3 ]
机构：
[1] CHU Amiens, Hop Sud, Serv Pharmacol Clin, F-80054 Amiens 1, France
[2] INSERM, U1088, Amiens, France
[3] CHU Amiens, Serv Cardiol, Amiens, France
来源：
ARCHIVES OF CARDIOVASCULAR DISEASES | 2013年 / 106卷 / 05期
关键词：
Drug induced valvular disease; Ergot alkaloids; Ergot-derived dopamine agonists; Norfenfluramine; Valvular regurgitation; APPETITE-SUPPRESSANT DRUGS; CARDIAC-VALVE REGURGITATION; PARKINSONS-DISEASE; BENFLUOREX THERAPY; DOPAMINE AGONISTS; TRICUSPID REGURGITATION; METHYSERGIDE THERAPY; INDUCED VALVULOPATHY; DIABETES-MELLITUS; FENFLURAMINE;
D O I：
10.1016/j.acvd.2013.02.003
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Numerous reports have shown an unquestionable association between fibrotic valve disease and the following drugs: ergot alkaloids (such as methysergide and ergotamine), ergot-derived dopaminergic agonists (such as pergolide and cabergoline) and drugs metabolized into norfenfluramine (such as fenfluramine, dexfenfluramine and benfluorex). This review focuses on different aspects of drug-induced valvular heart disease: historical background; echocardiographic features; different drugs recognized as being responsible for valvular heart disease; and pathophysiology. (C) 2013 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：333 / 339
页数：7
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