Advances in the Chemistry of Mannich Bases of Thiophenes and Furans

被引：14
作者：
Roman, Gheorghe [1 ]
机构：
[1] Petru Poni Inst Macromol Chem, Dept Inorgan Polymers, Iasi 700487, Romania
来源：
MINI-REVIEWS IN ORGANIC CHEMISTRY | 2013年 / 10卷 / 01期
关键词：
Aminomethylation; mannich reaction; mannich bases; thiophene; furan; drug design; AZAHETEROARYL-SUBSTITUTED 2,5-DIMETHYLPYRROLES; DIASTEREOSELECTIVE SYNTHESIS; PRIMARY AMINES; CHOLINERGIC PROPERTIES; BETA-AMINOMETHYLATION; STEREOCHEMICAL COURSE; RECEPTOR ANTAGONISTS; AROMATIC-COMPOUNDS; LAYERED COMPOUNDS; VINYLOGOUS ALDOL;
D O I：
10.2174/1570193X11310010003
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The advances in the chemistry of Mannich bases of electron-rich, monocyclic five-membered heterocycles with one heteroatom thiophene and furan are reviewed. The aminomethylation of these heterocycles along with the reactivity and the applications of their Mannich bases are summarized.
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页码：27 / 39
页数：13
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