Silver Solid Amalgam Electrode as a Tool for Monitoring the Electrochemical Reduction of Hydroxocobalamin

被引：31

作者：

Bandzuchova, Lenka ^{[1
]}

Selesovska, Renata ^{[1
]}

Navratil, Tomas ^{[2
]}

Chylkova, Jaromira ^{[1
]}

机构：

[1] Univ Pardubice, Fac Chem Technol, Inst Environm & Chem Engn, Pardubice 53210, Czech Republic

[2] AS CR, J Heyrovsky Inst Phys Chem, Vvi, Prague 18223 8, Czech Republic

来源：

ELECTROANALYSIS | 2013年 / 25卷 / 01期

关键词：

Cobalamin; Hanging mercury drop electrode; Silver solid amalgam electrode; Voltammetry; VOLTAMMETRIC DETERMINATION; LIQUID-CHROMATOGRAPHY; ELIMINATION VOLTAMMETRY; AMPEROMETRIC DETERMINATION; LINEAR SCAN; MERCURY; VITAMIN-B-12; DNA; VERIFICATION; ADSORPTION;

D O I：

10.1002/elan.201200365

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The voltammetric behavior of hydroxocobalamin (OH-Cbl), one form of vitamin B12, has been studied using two modifications of silver solid amalgam electrode: polished (p-AgSAE) and mercury meniscus modified (m-AgSAE). All results were compared with these achieved using hanging mercury drop electrode (HMDE). Various voltammetric methods, like cyclic voltammetry, DC voltammetry, differential pulse voltammetry and elimination voltammetry with linear scan, were applied to investigate the electrochemical behavior of OH-Cbl. Working conditions of differential pulse voltammetry were found and the achieved limits of detection (LD=1.5 nmol?L-1 (m-AgSAE) and 3.3 nmol?L-1 (p-AgSAE)) proved high sensitivity. The applicability of the proposed method was verified by analysis of vitamin preparation.

引用

页码：213 / 222

页数：10

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