GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations

被引：1070

作者：

Andrews, Jeff ^{[1
]}

Guyatt, Gordon ^{[2
,3
,4
]}

Oxman, Andrew D. ^{[5
]}

Alderson, Phil ^{[6
]}

Dahm, Philipp ^{[7
,8
]}

Falck-Ytter, Yngve ^{[9
]}

Nasser, Mona ^{[10
,11
]}

Meerpohl, Joerg ^{[12
,13
]}

Post, Piet N. ^{[14
]}

Kunz, Regina ^{[15
]}

Brozek, Jan ^{[2
,3
]}

Vist, Gunn ^{[5
]}

Rind, David ^{[16
,17
]}

Akl, Elie A. ^{[18
]}

Schuenemann, Holger J. ^{[2
,3
,4
]}

机构：

[1] Vanderbilt Univ, Vanderbilt Evidence Based Practice Ctr, Nashville, TN 37204 USA

[2] McMaster Univ, Dept Clin Epidemiol, Hamilton, ON L8N 3Z5, Canada

[3] McMaster Univ, Dept Biostat, Hamilton, ON L8N 3Z5, Canada

[4] McMaster Univ, Dept Med, Hamilton, ON L8N 3Z5, Canada

[5] Norwegian Knowledge Ctr Hlth Serv, N-0130 Oslo, Norway

[6] Natl Inst Hlth & Clin Excellence, Manchester M1 4BD, Lancs, England

[7] Univ Florida, Dept Urol, Coll Med, Gainesville, FL 32610 USA

[8] VA Med Ctr, Gainesville, FL 32610 USA

[9] Case Western Reserve Univ, Div Gastroenterol, Case & VA Med Ctr, Cleveland, OH 44106 USA

[10] Univ Exeter, Peninsula Coll Med & Dent, Plymouth PL6 8BU, Devon, England

[11] Univ Plymouth, Peninsula Coll Med & Dent, Plymouth PL6 8BU, Devon, England

[12] Univ Med Ctr Freiburg, German Cochrane Ctr, Inst Med Biometry & Med Informat, D-79110 Freiburg, Germany

[13] Univ Med Ctr Freiburg, Ctr Pediat & Adolescent Med, D-79106 Freiburg, Germany

[14] Post Voor Zorg, NL-2628 LC Delft, Netherlands

[15] Univ Basel Hosp, Acad Swiss Insurance Med, CH-4031 Basel, Switzerland

[16] Harvard Univ, Sch Med, Boston, MA USA

[17] UpToDate, Boston, MA USA

[18] SUNY Buffalo, Dept Med, Buffalo, NY 14260 USA

来源：

JOURNAL OF CLINICAL EPIDEMIOLOGY | 2013年 / 66卷 / 07期

关键词：

GRADE; Quality of evidence; Strength of evidence; Guideline development; Grading; Recommendations; ANTITHROMBOTIC THERAPY; FINDINGS TABLES; QUALITY; SUPERIOR; STRENGTH; UPDATE; TRIAL;

D O I：

10.1016/j.jclinepi.2012.03.013

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

This article describes the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to classifying the direction and strength of recommendations. The strength of a recommendation, separated into strong and weak, is defined as the extent to which one can be confident that the desirable effects of an intervention outweigh its undesirable effects. Alternative terms for a weak recommendation include conditional, discretionary, or qualified. The strength of a recommendation has specific implications for patients, the public, clinicians, and policy makers. Occasionally, guideline developers may choose to make "only-in-research" recommendations. Although panels may choose not to make recommendations, this choice leaves those looking for answers from guidelines without the guidance they are seeking. GRADE therefore encourages panels to, wherever possible, offer recommendations. (c) 2013 Published by Elsevier Inc.

引用

页码：719 / 725

页数：7

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