Effects of Autogenous Tooth Bone Graft and Platelet-Rich Fibrin in Peri-Implant Defects: An Experimental Study in an Animal Model

被引：8

作者：

Kizildag, Alper ^{[1
]}

Tasdemir, Ufuk ^{[2
]}

Arabaci, Taner ^{[3
]}

Kizildag, Canan Aksu ^{[4
]}

Albayrak, Mevlut ^{[5
]}

Sahin, Barbaros ^{[6
]}

机构：

[1] Pamukkale Univ, Fac Dent, Dept Periodontol, Denizli, Turkey

[2] Pamukkale Univ, Fac Dent, Dept Maxillofacial Surg, Denizli, Turkey

[3] Ataturk Univ, Fac Dent, Dept Periodontol, Erzurum, Turkey

[4] Pamukkale Univ, Fac Dent, Dept Orthodont, Denizli, Turkey

[5] Ataturk Univ, Hlth Serv Vocat Training Sch, Med Lab Dept, Erzurum, Turkey

[6] Pamukkale Univ, Expt Surg Applicat & Res Ctr, Denizli, Turkey

来源：

JOURNAL OF ORAL IMPLANTOLOGY | 2020年 / 46卷 / 03期

关键词：

bone formation; bone-implant interface; tooth graft; peri-implant defect; platelet-rich fibrin; CALCIUM-PHOSPHATE CERAMICS; GROWTH-FACTORS; DENTIN MATRIX; EXTRACTION SOCKETS; REGENERATION; EXPRESSION; PLACEMENT;

D O I：

10.1563/aaid-joi-D-19-00038

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The aim of this study was to evaluate the effect of autogenous tooth bone graft (ATBG) combined with platelet-rich fibrin (PRF) on bone healing in rabbit peri-implant osseous defects. Eighteen New Zealand rabbits were divided into 3 groups. Bone defects were prepared in each rabbit, and then an implant cavity was created in the defects. Dental implants were placed, and the peri-implant bone defects were treated with the following 3 methods: no graft material was applied in the control group, bone defects were treated with ATBG in the ATBG group, and bone defects were treated with ATBG combined with PRF in the ATBG+PRF group. After 28 days, the rabbits were sacrificed, and the dental implants with surrounding bone were removed. New bone formation and the percentage of bone-to-implant contact (BIC) were determined with histomorphometric evaluations. New bone formation was significantly higher in the ATBG+PRF group than the control and ATBG groups (P< .05). In addition, BIC was significantly higher in the ATBG+PRF group than in the control and ATBG groups (P< .05). The combination of ATBG with PRF contributed to bone healing in rabbits with peri-implant bone defects.

引用

页码：221 / 226

页数：6

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