The negative effects of obesity on heart, especially the electrophysiology of the heart

被引：12
作者：
Chen, Haishan [1 ]
Wang, Xin [1 ]
Xiong, Chongxiang [1 ]
Zou, Hequn [1 ]
机构：
[1] Southern Med Univ, Dept Nephrol, Affiliated Hosp 3, 183 West Zhongshan Ave, Guangzhou 510630, Peoples R China
来源：
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2020年 / 48卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Obesity; QT interval; ventricular re-polarisation; cardiovascular diseases; hypertension; diabetes; weight loss; LEFT-VENTRICULAR HYPERTROPHY; CARDIOVASCULAR RISK-FACTORS; LOW-DENSITY-LIPOPROTEIN; LONG QT SYNDROME; WEIGHT-LOSS; BARIATRIC SURGERY; ELECTROCARDIOGRAPHIC PARAMETERS; ENDOTHELIAL DYSFUNCTION; ARRHYTHMIA RISK; BLOOD-PRESSURE;
D O I：
10.1080/21691401.2020.1770269
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Obesity is associated with ventricular arrhythmia and sudden cardiac death. Numerous studies have shown that obesity may have effects on the heart by affecting the ventricular re-polarisation (VR). As an effective detection method for VR the measurement of the QT interval has been extensively studied in obese patients (OP). This review aims to investigate the relationship between obesity and obesity-related diseases; including diabetes, hypertension and cardiovascular diseases (CVD). This review compares the advantages and disadvantages of different QT interval measurement methods, as well as explores the possible mechanisms of obesity leading to heart disease. Finally, it also reviews the feasibility of various weight loss methods to reverse the risk of obesity leading to heart disease is discussed.
引用
收藏
页码：1055 / 1062
页数：8
相关论文
共 106 条
[61]  
Mizia-Stec K, 1999, Pol Arch Med Wewn, V101, P391
[62]  
Mshui ME, 1999, P SOC EXP BIOL MED, V220, P133, DOI 10.1046/j.1525-1373.1999.d01-20.x
[63]   Relation of Left Ventricular Mass to QTc in Normotensive Severely Obese Patients [J].
Mukerji, Rita ;
Terry, Boyd E. ;
Fresen, John L. ;
Petruc, Marius ;
Govindarajan, Gurushankar ;
Alpert, Martin A. .
OBESITY, 2012, 20 (09) :1950-1954
[64]   Effect of Weight Loss After Bariatric Surgery on Left Ventricular Mass and Ventricular Repolarization in Normotensive Morbidly Obese Patients [J].
Mukerji, Rita ;
Petruc, Marius ;
Fresen, John L. ;
Terry, Boyd E. ;
Govindarajan, Gurushankar ;
Alpert, Martin A. .
AMERICAN JOURNAL OF CARDIOLOGY, 2012, 110 (03) :415-419
[65]   Relationship between anthropometric measures and early electrocardiographic changes in obese rats [J].
Mutiso S.K. ;
Rono D.K. ;
Bukachi F. .
BMC Research Notes, 7 (1)
[66]   Global, regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Disease Study 2013 [J].
Ng, Marie ;
Fleming, Tom ;
Robinson, Margaret ;
Thomson, Blake ;
Graetz, Nicholas ;
Margono, Christopher ;
Mullany, Erin C. ;
Biryukov, Stan ;
Abbafati, Cristiana ;
Abera, Semaw Ferede ;
Abraham, Jerry P. ;
Abu-Rmeileh, Niveen M. E. ;
Achoki, Tom ;
AlBuhairan, Fadia S. ;
Alemu, Zewdie A. ;
Alfonso, Rafael ;
Ali, Mohammed K. ;
Ali, Raghib ;
Alvis Guzman, Nelson ;
Ammar, Walid ;
Anwari, Palwaslia ;
Banerjee, Amitava ;
Barquera, Simon ;
Basu, Sanjay ;
Bennett, Derrick A. ;
Bhutta, Zulfiqar ;
Blore, Jed ;
Cabral, Norberto ;
Campos Nonato, Ismael ;
Chang, Jung-Chen ;
Chowdhury, Rajiv ;
Courville, Karen J. ;
Criqui, Michael H. ;
Cundiff, David K. ;
Dabhadkar, Kaustubh C. ;
Dandona, Lalit ;
Davis, Adrian ;
Dayama, Anand ;
Dharmaratne, Samath D. ;
Ding, Eric L. ;
Durrani, Adnan M. ;
Esteghamati, Alireza ;
Farzadfar, Farshad ;
Fay, Derek F. J. ;
Feigin, Valery L. ;
Flaxman, Abraham ;
Forouzanfar, Mohammad H. ;
Goto, Atsushi ;
Green, Mark A. ;
Gupta, Rajeev .
LANCET, 2014, 384 (9945) :766-781
[67]   Obesity does not influence electrocardiographic parameters in coronary patients [J].
Nomura, A ;
Zareba, W ;
Moss, AJ .
AMERICAN JOURNAL OF CARDIOLOGY, 2000, 85 (01) :106-+
[68]   Effect of obesity and weight loss on ventricular repolarization: a systematic review and meta-analysis [J].
Omran, J. ;
Firwana, B. ;
Koerber, S. ;
Bostick, B. ;
Alpert, M. A. .
OBESITY REVIEWS, 2016, 17 (06) :520-530
[69]   Obesity and Ventricular Repolarization: a Comprehensive Review [J].
Omran, Jad ;
Bostick, Brian P. ;
Chan, Albert K. ;
Alpert, Martin A. .
PROGRESS IN CARDIOVASCULAR DISEASES, 2018, 61 (02) :124-135
[70]   Adiponectin, an adipocyte-derived plasma protein, inhibits endothelial NF-κB signaling through a cAMP-dependent pathway [J].
Ouchi, N ;
Kihara, S ;
Arita, Y ;
Okamoto, Y ;
Maeda, K ;
Kuriyama, H ;
Hotta, K ;
Nishida, M ;
Takahashi, M ;
Muraguchi, M ;
Ohmoto, Y ;
Nakamura, T ;
Yamashita, S ;
Funahashi, T ;
Matsuzawa, Y .
CIRCULATION, 2000, 102 (11) :1296-1301
234567891011