Dasatinib-induced colitis: discovering the side effects of immunotherapy

被引:3
作者
Jimenez Beltran, Victor [1 ]
Bermudez Alarcon, Maria Auxiliadora [2 ]
Castano Fernandez, Olegario [1 ]
机构
[1] Hosp Univ Cent Asturias, Dept Gastroenterol & Hepatol, Oviedo, Spain
[2] Hosp Univ Cent Asturias, Dept Pathol, Oviedo, Spain
关键词
Dasatinib; Colitis; Fecal occult blood test;
D O I
10.17235/reed.2020.6789/2019
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The effects of immunotherapy are numerous and are still being discovered. We present a case report of a patient who received dasatinib for chronic myeloid leukemia. A colonoscopy was performed due to a positive fecal occult blood test and colitis was observed. Furthermore, she also had a cytomegalovirus infection. This case highlights the importance to detect cases of immunomodulatory drugs induced colitis by the fecal occult blood test.
引用
收藏
页码:663 / +
页数:2
相关论文
共 5 条
[1]   Cytomegalovirus Colitis during Dasatinib Treatment for Patients with Hematologic Malignancy: Case Series and Literature Review [J].
Choi, Jae-Ki ;
Cho, Sung-Yeon ;
Choi, Su-Mi ;
Kim, Gyo Hui ;
Lee, Sung-Eun ;
Lee, Seok ;
Kim, Dong-Wook ;
Lee, Dong-Gun .
INFECTION AND CHEMOTHERAPY, 2018, 50 (02) :153-159
[2]   Ipilimumab-induced colitis: A new challenge for gastroenterologists [J].
Mesonero, Francisco ;
Lopez-Sanroman, Antonio ;
Madariaga, Ainhoa ;
Soria, Ainara .
GASTROENTEROLOGIA Y HEPATOLOGIA, 2016, 39 (03) :233-238
[3]   Long-term follow-up of lower dose dasatinib (50 mg daily) as frontline therapy in newly diagnosed chronic-phase chronic myeloid leukemia [J].
Naqvi, Kiran ;
Jabbour, Elias ;
Skinner, Jeffrey ;
Anderson, Kristin ;
Dellasala, Sara ;
Yilmaz, Musa ;
Ferrajoli, Alessandra ;
Bose, Prithviraj ;
Thompson, Philip ;
Alvarado, Yesid ;
Jain, Nitin ;
Takahashi, Koichi ;
Burger, Jan ;
Estrov, Zeev ;
Borthakur, Gautam ;
Pemmaraju, Naveen ;
Paul, Shilpa ;
Cortes, Jorge ;
Kantarjian, Hagop M. .
CANCER, 2020, 126 (01) :67-75
[4]   Clinical efficacy of fecal occult blood test and colonoscopy for dasatinib-induced hemorrhagic colitis in CML patients [J].
Nishiwaki, Satoshi ;
Maeda, Matsuyoshi ;
Yamada, Masahiro ;
Okuno, Shingo ;
Harada, Yasuhiko ;
Suzuki, Kotaro ;
Kurahashi, Shingo ;
Urano, Fumihiro ;
Okamura, Shozo ;
Sugiura, Isamu .
BLOOD, 2017, 129 (01) :126-128
[5]   Analysis of adverse events associated with dasatinib and nilotinib treatments in chronic-phase chronic myeloid leukemia patients outside clinical trials [J].
Suh, Koung Jin ;
Lee, Ji Yun ;
Shin, Dong-Yeop ;
Koh, Youngil ;
Bang, Soo-Mee ;
Yoon, Sung-Soo ;
Park, Seonyang ;
Kim, Inho ;
Lee, Jeong-Ok .
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2017, 106 (02) :229-239