Positively charged silver nanoparticles and their effect on surface-enhanced Raman scattering of dye-labelled oligonucleotides

被引:82
作者
van Lierop, Danny [1 ]
Krpetic, Zeljka [1 ]
Guerrini, Luca [1 ]
Larmour, Iain A. [1 ]
Dougan, Jennifer A. [1 ]
Faulds, Karen [1 ]
Graham, Duncan [1 ]
机构
[1] Univ Strathclyde, Dept Pure & Appl Chem, Ctr Mol Nanometrol, WestCHEM, Glasgow G1 1XL, Lanark, Scotland
基金
英国工程与自然科学研究理事会;
关键词
DNA; GOLD; SERS; SPERMINE;
D O I
10.1039/c2cc31731a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Improved positively charged nanoparticles are described to provide a simplified SERS substrate for DNA detection. Complete flocculation of the nanoparticles is prevented due to the controlled analyte induced aggregation. This provides a stable aggregation state which significantly extends the analysis window simplifying DNA detection by SERS.
引用
收藏
页码:8192 / 8194
页数:3
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