Cyclic guanidines. Part 6. Synthesis of benzimidazoles by intramolecular vicarious nucleophilic substitution of hydrogen

被引：25

作者：

Esser, F ^{[1
]}

Ehrengart, P ^{[1
]}

Ignatow, HP ^{[1
]}

机构：

[1] Boehringer Ingelheim GmbH & Co KG, Dept Med Chem, D-55216 Ingelheim, Germany

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 09期

关键词：

D O I：

10.1039/a900553f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

m-Nitrophenylguanidines, which carry a vicarious leaving group, cyclize under basic conditions yielding nitro-benzimidazoles. Preliminary observations of the regioselectivity of the ring closure reaction are reported.

引用

页码：1153 / 1154

页数：2

共 16 条

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