Coexistence of squamous cell tracheal papilloma and carcinoma treated with chemotherapy and radiotherapy: a case report

被引：1

作者：

Paliouras, Dimitrios ^{[1
]}

Gogakos, Apostolos ^{[1
]}

Rallis, Thomas ^{[1
]}

Chatzinikolaou, Fotios ^{[2
]}

Asteriou, Christos ^{[1
]}

Tagarakis, Georgios ^{[3
]}

Organtzis, John ^{[4
]}

Tsakiridis, Kosmas ^{[5
]}

Tsavlis, Drosos ^{[4
]}

Zissimopoulos, Athanasios ^{[6
]}

Kioumis, Ioannis ^{[4
]}

Hohenforst-Schmidt, Wolfgang ^{[7
]}

Zarogoulidis, Konstantinos ^{[4
]}

Zarogoulidis, Paul ^{[4
]}

Barbetakis, Nikolaos ^{[1
]}

机构：

[1] AHEPA Univ Hosp, Dept Thorac Surg, Theagenio Canc Hosp, Thessaloniki, Greece

[2] AHEPA Univ Hosp, Dept Forens Med & Toxicol, Fac Med, Thessaloniki, Greece

[3] AHEPA Univ Hosp, Dept Cardiothorac Surg, Thessaloniki, Greece

[4] Aristotle Univ Thessaloniki, Dept Pulm, Oncol Unit, G Papanikolaou Gen Hosp, Thessaloniki 1100, Greece

[5] St Luke Private Hosp, Dept Cardiothorac Surg, Thessaloniki, Greece

[6] Democritus Univ Thrace, Univ Gen Hosp Alexandroupolis, Nucl Med Dept, Alexandroupolis, Greece

[7] Univ Erlangen Nurnberg, Med Clin 1, Fuerth Hosp, Furth, Germany

来源：

THERAPEUTICS AND CLINICAL RISK MANAGEMENT | 2016年 / 12卷

关键词：

papilloma; trachea; squamous cell carcinoma; RECURRENT RESPIRATORY PAPILLOMATOSIS; TRANSFORMATION; P53; DNA;

D O I：

10.2147/TCRM.S95233

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Background: Papillomatosis presents, most frequently, as multiple lesions of the respiratory tract, which are usually considered benign. Malignant degeneration into squamous cell carcinoma is quite common, although curative approaches vary a lot in modern literature. Case report: We report a case of a 66-year-old male patient with the coexistence of multiple squamous cell papilloma and carcinoma in the upper trachea with severe airway obstruction that was diagnosed through bronchoscopy and treated by performing an urgent tracheostomy, followed by concurrent chemotherapy and radiotherapy. There was no evidence of recurrence after a 12-month follow-up period. Conclusion: This study underlines the diagnostic and therapeutic value of bronchoscopy as well as multimodality palliative treatment in such cases. To the best of our knowledge, this is the first study to describe an immediate treatment protocol with tracheostomy and concurrent chemotherapy/radiotherapy in a patient with squamous cell tracheal papilloma and carcinoma.

引用

页码：1 / 3

页数：3

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