Molecular diagnosis of Saksenaea vasiformis cutaneous infection after scorpion sting in an immunocompetent adolescent

被引:33
作者
Lechevalier, Pauline [1 ,2 ]
Hermoso, Dea Garcia [3 ]
Carol, Agnes [2 ]
Bonacorsi, Stephane [2 ]
Ferkdadji, Latifa [4 ]
Fitoussi, Franck [5 ]
Lortholary, Olivier [3 ,6 ]
Bourrillon, Antoine [1 ]
Faye, Albert [1 ]
Dannaoui, Eric [3 ,7 ]
Angoulvant, Francois [1 ]
机构
[1] Univ Paris 07, Hop Robert Debre, AP HP, Serv Pediat Gen, F-75019 Paris, France
[2] Univ Paris 07, Hop Robert Debre, AP HP, Microbiol Lab, F-75019 Paris, France
[3] Inst Pasteur, CNRS, Ctr Natl Reference Mycol & Antifong, Unite Mycol Mol,URA3012, Paris, France
[4] Univ Paris 07, Hop Robert Debre, AP HP, Serv Anatomopathol, F-75019 Paris, France
[5] Univ Paris 07, Hop Robert Debre, AP HP, Serv Chirurg Orthoped, F-75019 Paris, France
[6] Univ Paris 05, Hop Necker Enfants Malad, AP HP, Ctr Infectiol Necker Pasteur, Paris, France
[7] Univ Paris 05, Hop Georges Pampidou, AP HP, Unite Parasitol Mycol, Paris, France
关键词
D O I
10.1128/JCM.00052-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report the first case of cutaneous mucormycosis after a scorpion sting in Tunisia. Histopathology showed broad aseptate hyphae suggestive of a Zygomycete. Saksenaea vasiformis was identified by PCR amplification and sequencing of the fungal DNA on a cutaneous biopsy. Successful treatment was obtained by surgery and liposomal amphotericin B.
引用
收藏
页码:3169 / 3172
页数:4
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