Augmentation index and pulse wave velocity as indicators of cardiovascular stiffness

被引:21
作者
Nakae, Ichiro [1 ]
Matsuo, Shinro [1 ]
Matsumoto, Tetsuya [1 ]
Mitsunami, Kenichi [2 ]
Horie, Minoru [1 ]
机构
[1] Shiga Univ Med Sci, Dept Cardiovasc & Resp Med, Otsu, Shiga 5202192, Japan
[2] Shiga Univ Med Sci, Dept Gen Med, Otsu, Shiga 5202192, Japan
关键词
augmentation index; pulse wave velocity; diastolic function;
D O I
10.1177/0003319707306299
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
The authors examine the clinical significance of radial augmentation index (rAI) and brachial-ankle Pulse wave velocity (baPWW). In 78 hypertensive patients, rAI correlates inversely with pulse rate (PR; r = -0.57, P < .001), but baPWV does not. A weak correlation between rAI and systolic blood pressure (SBP) is observed (r = 0.28, P <. 05). rAI has no significant correlation with diastolic blood pressure (DBP). In contrast, baPWV correlates positively with both SBP (r = 0.54, P < .001) and DBP (r = 0,43, P < .001). In 56 of these patients, baPMV correlates with the diastolic parameters-the mitral E/A ratio (r = -0.35, P < .01), pulmonary vein S/D ratio (r = 0.41, P < .01), and deceleration time 0.28, P < .05) by echocardiography, but AI.P75 (rAI corrected for PR 75 bpm because of PR dependence) does not. Therefore, for detection of diastolic dysfunction, baPWV may be more sensitive than rAI.
引用
收藏
页码:421 / 426
页数:6
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