Transgender Medicine and Risk of Venous Thromboembolism

被引：5

作者：

Van Bunderen, C. C. ^{[1
]}

Leentjens, J. ^{[2
]}

Middeldorp, S. ^{[2
]}

机构：

[1] Radboud Univ Nijmegen Med Ctr, Dept Internal Med, Div Endocrinol, Nijmegen, Netherlands

[2] Radboud Univ Nijmegen Med Ctr, Radboud Inst Hlth Sci RIHS, Dept Internal Med, Div Vasc Med, Nijmegen, Netherlands

来源：

HAMOSTASEOLOGIE | 2022年 / 42卷 / 05期

关键词：

transgender; hormone replacement therapy; venous thromboembolism; venous thrombosis; pulmonary embolism; HORMONE REPLACEMENT THERAPY; POSTMENOPAUSAL WOMEN; TRANSSEXUAL SUBJECTS; CYPROTERONE-ACETATE; EXTENDED TREATMENT; ESTROGEN; THROMBOSIS; COMPLICATIONS; METAANALYSIS; MORTALITY;

D O I：

10.1055/a-1891-8158

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Gender dysphoria refers to psychological distress that results from an incongruence between gender identity and sex assigned at birth. Administration of sex hormones is most often used as a first step to develop and maintain physical characteristics consistent with gender identity. Gender-affirming hormone treatment is considered beneficial for the quality of life and reduction of depression. However, estrogen and androgen-lowering hormone therapies used in transwomen are in particular associated with increased risk of venous thromboembolism. In this review, introduced by a clinical case, we provide an overview of the currently available medical therapies in transgender medicine, and put the associated increased risk of venous thromboembolism into perspective.

引用

页码：301 / 307

页数：7

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