The Influence of Na and Ti on the In Vitro Degradation and Bioactivity in 58S Sol-Gel Bioactive Glass

被引:12
作者
Ni, Shirong [1 ]
Du, Ruilin [2 ]
Ni, Siyu [2 ,3 ]
机构
[1] Wenzhou Med Coll, Dept Pathophysiol, Wenzhou 325035, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Ceram, Biomat & Tissue Engn Res Ctr, Shanghai 200050, Peoples R China
[3] Donghua Univ, Coll Chem Chem Engn & Biotechnol, Shanghai 201620, Peoples R China
关键词
MEDICAL APPLICATIONS; MAGNESIUM; BEHAVIOR; SODIUM;
D O I
10.1155/2012/730810
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
The aim of this study was to investigate the effect of Na and Ti on the in vitro degradation and bioactivity in the 58S bioactive glass. The degradation was evaluated through the activation energy of Si ion release from bioactive glasses and the weight loss of bioactive glasses in Tris-HCl buffer solution. The in vitro bioactivity of the bioactive glasses was investigated by analysis of apatite-formation ability in the simulated body fluid (SBF). The results showed that Na in the 58S glass accelerated the dissolution rate of the glass, whereas Ti in the 58S glass slowed down the rate of glass solubility. Bioactivity tests showed that Na in glass increased the apatite-forming ability in SBF. In contrast, Ti in glass retards the apatite formation at the initial stage of SBF soaking but does not affect the growth of apatite after long periods of soaking.
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页数:7
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