Cellular orchestrators of renal fibrosis

被引：42

作者：

Conway, B. ^{[1
]}

Hughes, J. ^{[1
]}

机构：

[1] Univ Edinburgh, Queens Med Res Inst, MRC Ctr Inflammat Res, Edinburgh EH16 4TJ, Midlothian, Scotland

来源：

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE | 2012年 / 105卷 / 07期

关键词：

MACROPHAGES; PROGRESSION; FIBROBLASTS; MONOCYTE; COLLAGEN; REPAIR; TARGET; EMT;

D O I：

10.1093/qjmed/hcr235

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

引用

页码：611 / 615

页数：5

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