Highly selective and sensitive fluorescence turn-on probe for a catalytic amount of Cu(I) ions in water through the click reaction

被引：22

作者：

Park, Seokan ^{[1
]}

Kim, Hae-Jo ^{[1
]}

机构：

[1] Hankuk Univ Foreign Studies, Dept Chem, Yongin 449719, South Korea

来源：

TETRAHEDRON LETTERS | 2012年 / 53卷 / 33期

基金：

新加坡国家研究基金会;

关键词：

Catalytic; Click reaction; Copper ion; Coumarin; Fluorescence; NEWLY SYNTHESIZED PROTEINS; NEURODEGENERATIVE DISEASES; CHEMOSENSORS; SENSOR; VISUALIZATION; MECHANISMS; CYANIDE; DESIGN; CELLS;

D O I：

10.1016/j.tetlet.2012.06.079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple azide-functionalized coumarin (1) was utilized as a fluorescence turn-on probe for a catalytic amount of Cu(I) ions in HEPES buffer. The probe has shown a selective and sensitive response to the cuprous ions over other various cations through a Cu(I)-mediated click reaction of 1 to an alkyne. When a catalytic amount of copper sulfates was added in the presence of ascorbate, the prominent fluorescence 'Off-On' change of 1 was observed so that submicromolar concentration of copper ions was detectable by the naked eye. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：4473 / 4475

页数：3

共 28 条

[1] Luminescence lifetime-based sensor for cyanide and related anions [J].

Anzenbacher, P ;

Tyson, DS ;

Jursíková, K ;

Castellano, FN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (22) :6232-6233

[2] Metals in Alzheimer's and Parkinson's diseases [J].

Barnham, Kevin J. ;

Bush, Ashley I. .

CURRENT OPINION IN CHEMICAL BIOLOGY, 2008, 12 (02) :222-228

[3] Neurodegenerative diseases and oxidative stress [J].

Barnham, KJ ;

Masters, CL ;

Bush, AI .

NATURE REVIEWS DRUG DISCOVERY, 2004, 3 (03) :205-214

[4] Selective dye-labeling of newly synthesized proteins in bacterial cells [J].

Beatty, KE ;

Xie, F ;

Wang, Q ;

Tirrell, DA .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (41) :14150-14151

[5] Fluorescence visualization of newly synthesized proteins in mammalian cells [J].

Beatty, Kimberly E. ;

Liu, Julie C. ;

Xie, Fang ;

Dieterich, Daniela C. ;

Schuman, Erin M. ;

Wang, Qian ;

Tirrell, David A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (44) :7364-7367

[6] Biological inorganic and bioinorganic chemistry of neurodegeneration based on prion and Alzheimer diseases [J].

Brown, DR ;

Kozlowski, H .

DALTON TRANSACTIONS, 2004, (13) :1907-1917

[7] A highly selective cyanide sensing in water via fluorescence change and its application to in vivo imaging [J].

Chung, So-Young ;

Nam, Seong-Won ;

Lim, Jeesun ;

Park, Sungsu ;

Yoon, Juyoung .

CHEMICAL COMMUNICATIONS, 2009, (20) :2866-2868

[8] Metal based neurodegenerative diseases - From molecular mechanisms to therapeutic strategies [J].

Crichton, Robert R. ;

Dexter, D. T. ;

Ward, Roberta J. .

COORDINATION CHEMISTRY REVIEWS, 2008, 252 (10-11) :1189-1199

[9]

Grandini P, 1999, ANGEW CHEM INT EDIT, V38, P3061, DOI 10.1002/(SICI)1521-3773(19991018)38:20<3061::AID-ANIE3061>3.0.CO

[10]

2-A

← 1 2 3 →