Relationship between serum 25-hydroxy vitamin D levels and retinopathy of prematurity
被引:17
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作者:
Kabatas, Emrah Utku
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Dr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Kabatas, Emrah Utku
[1
]
Dinlen, Nurdan Fettah
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Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Dinlen, Nurdan Fettah
[2
]
Zenciroglu, Aysegul
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机构:
Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Zenciroglu, Aysegul
[2
]
Dilli, Dilek
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Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Dilli, Dilek
[2
]
Beken, Serdar
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Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Beken, Serdar
[2
]
Okumus, Nurullah
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Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, TurkeyDr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
Okumus, Nurullah
[2
]
机构:
[1] Dr Sami Ulus Matern & Children Res & Training Hos, Dept Ophtalmol, TR-06080 Ankara, Turkey
[2] Dr Sami Ulus Matern & Children Res & Training Hos, Dept Neonatol, Ankara, Turkey
Preterm;
retinopathy of prematurity;
vitamin D;
MACULAR DEGENERATION;
RISK-FACTORS;
D DEFICIENCY;
IN-VIVO;
ANGIOGENESIS;
D-3;
CALCITRIOL;
CHILDREN;
CANCER;
D O I:
10.1177/0036933017701867
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
Aim: To evaluate the relationship between serum 25-hydroxy vitamin D, 25 (OH) D, levels and retinopathy of prematurity. Methods and Results: Serum 25 (OH) D levels were measured in 97 very low birth weight infants, prior to vitamin D supplementation. The development of retinopathy of prematurity and its treatment requirement were evaluated. At follow-up, retinopathy of prematurity developed in 71 (73.2%) infants. Serum 25 (OH) D levels were significantly lower in infants with retinopathy of prematurity than ones without retinopathy of prematurity (P<0.001). The infants who required treatment had lower 25 (OH) D levels compared with the infants who did not required treatment (7.1 +/- 5.2ng/ml vs. 11.9 +/- 6.5ng/ml; P=0.003). Multivariate analysis showed that lower serum 25 (OH) D levels may be a risk factor for retinopathy of prematurity development [OR: 1.14, 95% CI (1.02-1.27), P=0.02]. Conclusion: Lower 25 (OH) D levels in the first days of life may be related to retinopathy of prematurity development and treatment requirement in premature infants.
机构:
Brown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Haddow, James E.
Neveux, Louis M.
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机构:
Brown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Neveux, Louis M.
Palomaki, Glenn E.
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机构:
Brown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Palomaki, Glenn E.
Lambert-Messerlian, Geralyn
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机构:
Brown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Lambert-Messerlian, Geralyn
Canick, Jacob A.
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机构:
Brown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Canick, Jacob A.
Grenache, David G.
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机构:
Univ Utah, Sch Med, Dept Pathol, Salt Lake City, UT USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA
Grenache, David G.
Lu, Jun
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机构:
ARUP Inst Clin & Expt Pathol, Salt Lake City, UT USABrown Univ, Alpert Med Sch, Women & Infants Hosp, Div Med Screening & Special Testing,Dept Pathol &, Providence, RI 02903 USA