Zinc Inhibits Human Islet Amyloid Polypeptide (IAPP) Amyloidogenesis

被引：0
|
作者：
Hartman, Kevin [1 ]
Brender, Jeffrey R. [1 ]
Subramanian, Vivekanandan [1 ]
Youngstrom, Daniel W. [1 ]
Ramamoorthy, Ayyalusamy [1 ]
机构：
[1] Univ Michigan, Ann Arbor, MI 48109 USA
来源：
BIOPHYSICAL JOURNAL | 2010年 / 98卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2009.12.1388
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：255A / 255A
页数：1
相关论文
共 50 条
  • [31] An in vitro model of early islet amyloid polypeptide (IAPP) fibrillogenesis using human IAPP-transgenic mouse islets
    Henson, M. S.
    Buman, B. L.
    Jordan, K.
    Rahrmann, E. P.
    Hardy, R. M.
    Johnson, K. H.
    O'Brien, T. D.
    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2006, 13 (04): : 250 - 259
  • [32] Molecular dynamics simulation on the inhibition mechanism of peptide-based inhibitor of islet amyloid polypeptide (IAPP) to islet amyloid polypeptide (IAPP22-28) oligomers
    Zhou, Shuangyan
    Wang, Qianqian
    Ren, Mengdan
    Zhang, Ai
    Liu, Huanxiang
    Yao, Xiaojun
    CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 90 (01) : 31 - 39
  • [33] Design of a mimic of nonamyloidogenic and bioactive human islet amyloid polypeptide (IAPP) as nanomolar affinity inhibitor of IAPP cytotoxic fibrillogenesis
    Yan, LM
    Tatarek-Nossol, M
    Velkova, A
    Kazantzis, A
    Kapurniotu, A
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (07) : 2046 - 2051
  • [34] Zinc stabilization of prefibrillar oligomers of human islet amyloid polypeptide
    Brender, Jeffrey R.
    Krishnamoorthy, Janarthanan
    Messina, Grazia M. L.
    Deb, Aniruddha
    Vivekanandan, Subramanian
    La Rosa, Carmelo
    Penner-Hahn, James E.
    Ramamoorthy, Ayyalusamy
    CHEMICAL COMMUNICATIONS, 2013, 49 (32) : 3339 - 3341
  • [35] Aggregation of islet amyloid polypeptide (IAPP): At what stage does IAPP become sticky and toxic?
    Rawat, A.
    Bhowmik, D.
    Das, A. K.
    Pandit, R.
    Maiti, S.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2015, 44 : S208 - S208
  • [36] Annexin V protects β-cells from human islet amyloid polypeptide (IAPP) induced apoptosis
    Ritzel, R
    Jayasinghe, S
    Langen, R
    Butler, P
    DIABETES, 2003, 52 : A356 - A356
  • [37] Screening of Inhibitors for β-Amyloid (Aβ) and Human Islet Amyloid Polypeptide (IAPP) Aggregation from Atlantic Canada Plant Extracts
    Yin, Fei
    Liu, Jianhui
    Ji, X.
    Wang, Yanwen
    Zidichouski, Jeffrey
    Zhang, Junzeng
    PHARMACEUTICAL BIOLOGY, 2010, 48 : 14 - 14
  • [38] Molecular Dynamics Simulations of Human Islet Amyloid Polypeptide (IAPP) Oligomers and their Interactions with Lipid Bilayers
    Zhao, Jun
    Yu, Xiang
    Zhao, Chao
    Wang, Qiuming
    Zheng, Jie
    BIOPHYSICAL JOURNAL, 2011, 100 (03) : 200 - 201
  • [39] Inhibitory effect of Pax4 on the human insulin and islet amyloid polypeptide (IAPP) promoters
    Campbell, SC
    Cragg, H
    Elrick, LJ
    Macfarlane, WM
    Shennan, KIJ
    Docherty, K
    FEBS LETTERS, 1999, 463 (1-2): : 53 - 57
  • [40] Ferret islet amyloid polypeptide (IAPP): characterization of in vitro and in vivo amyloidogenicity
    Paulsson, Johan F.
    Benoit-Biancamano, Marie-Odile
    Schaffer, Lauge
    Dahl, Kirsten
    AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS, 2011, 18 (04): : 222 - 228
12345