Justicidin A inhibits AKT/mTOR and activates type III PI3K/beclin 1 signaling pathways leading to autophagy of human colorectal cancer cells

被引：0
|
作者：
Su, Chun-Li [1 ,2 ]
Yen, Cheng-Hsin [2 ]
Lin, Chun-Nan [3 ]
Won, Shen-Jeu [4 ]
机构：
[1] Natl Taiwan Normal Univ, Dept Human Dev & Family Studies, Taipei, Taiwan
[2] Chang Jung Christian Univ, Dept Nursing, Tainan, Taiwan
[3] Kaohsiung Med Univ, Sch Pharm, Kaohsiung, Taiwan
[4] Natl Cheng Kung Univ, Coll Med, Dept Microbiol & Immunol, Tainan 70101, Taiwan
来源：
FASEB JOURNAL | 2010年 / 24卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Compartmentalized PI3K/Akt/mTOR Signaling in Living Cells
    Zhang, Jin
    FASEB JOURNAL, 2015, 29
  • [32] 1-Methoxyerythrabyssin II Induces Autophagy in Leukemia Cells via PI3K/Akt/mTOR Pathways
    Fang, Bo
    Kim, Soeun
    Kim, Yebon
    Qiu, Yinda
    Lee, Chang-Min
    Lai, Yinshuang
    Liu, Zhiguo
    Wang, Kun
    Cho, Namki
    PLANTA MEDICA, 2023, 89 (13) : 1204 - 1214
  • [33] HMGCL activates autophagy in osteosarcoma through β-HB mediated inhibition of the PI3K/AKT/mTOR signaling pathway
    Liu, Wenda
    Xia, Kezhou
    Huang, Xinghan
    Wei, Zhun
    Wei, Zicheng
    Wang, Xingyu
    Xiong, Chen
    Guo, Weichun
    JOURNAL OF TRANSLATIONAL MEDICINE, 2025, 23 (01)
  • [34] Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
    Renjie Zhang
    Zijian Wang
    Wenjie You
    Fengfang Zhou
    Zicheng Guo
    Kaiyu Qian
    Yu Xiao
    Xinghuan Wang
    Cancer Cell International, 20
  • [35] Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
    Zhang, Renjie
    Wang, Zijian
    You, Wenjie
    Zhou, Fengfang
    Guo, Zicheng
    Qian, Kaiyu
    Xiao, Yu
    Wang, Xinghuan
    CANCER CELL INTERNATIONAL, 2020, 20 (01)
  • [36] Icariin inhibits the growth of human cervical cancer cells by inducing apoptosis and autophagy by targeting mTOR/PI3K/AKT signalling pathway
    Huang, Shenjiao
    Xie, Tingting
    Liu, Wenjie
    JOURNAL OF BUON, 2019, 24 (03): : 990 - 996
  • [37] Piperlongumine inhibits growth potential of gastric cancer cells by targeting PI3K/Akt/mTOR signaling pathway
    Shrivastava, S.
    Jeengar, M. K.
    Thummuri, D.
    Naidu, V. G. M.
    EUROPEAN JOURNAL OF CANCER, 2014, 50 : S9 - S9
  • [38] Lomerizine 2HCl inhibits cell proliferation and induces protective autophagy in colorectal cancer via the PI3K/Akt/mTOR signaling pathway
    Tan, Xiang-Peng
    He, Yan
    Huang, Yun-Na
    Zheng, Can-Can
    Li, Jun-Qi
    Liu, Qin-Wen
    He, Ming-Liang
    Li, Bin
    Xu, Wen-Wen
    MEDCOMM, 2021, 2 (03): : 453 - 466
  • [39] Growth Factors, PI3K/AKT/mTOR and MAPK Signaling Pathways in Colorectal Cancer Pathogenesis: Where Are We Now?
    Stefani, Constantin
    Miricescu, Daniela
    Stanescu-Spinu, Iulia-Ioana
    Nica, Remus Iulian
    Greabu, Maria
    Totan, Alexandra Ripszky
    Jinga, Mariana
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (19)
  • [40] THADA inhibits autophagy and increases 5-FU sensitivity in gastric cancer cells via the PI3K/AKT/mTOR signaling pathway
    Lin, Xianke
    Pan, Jiajia
    Hamoudi, Hammza
    Yu, Jiren
    IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES, 2024, 27 (02) : 195 - 202
12345