Membrane curvature: How BAR domains bend bilayers

被引:148
作者
Zimmerberg, J [1 ]
McLaughlin, S
机构
[1] NICHHD, Lab Cellular & Mol Biophys, NIH, Bethesda, MD 20892 USA
[2] SUNY Stony Brook, Hlth Sci Ctr, Dept Physiol & Biophys, Stony Brook, NY 11794 USA
关键词
D O I
10.1016/j.cub.2004.02.060
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
An important new structure suggests the BAR domain is a membrane-binding module that can both produce and sense membrane curvature. BAR resembles a banana that binds membranes electrostatically through its positively charged, concave surface.
引用
收藏
页码:R250 / R252
页数:3
相关论文
共 18 条
  • [1] Lipid packing sensed by ArfGAP1 couples COPI coat disassembly to membrane bilayer curvature
    Bigay, J
    Gounon, P
    Robineau, S
    Antonny, B
    [J]. NATURE, 2003, 426 (6966) : 563 - 566
  • [2] BOAL D, 2002, MECH CELL, P156
  • [3] Protein-lipid interplay in fusion and fission of biological membranes
    Chernomordik, LV
    Kozlov, MM
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 2003, 72 : 175 - 207
  • [4] DILL KA, 2003, MOL DRIVING FORCES, pCH20
  • [5] DINITTO JP, 2003, SCI STKE
  • [6] Reprogramming control of an allosteric signaling switch through modular recombination
    Dueber, JE
    Yeh, BJ
    Chak, K
    Lim, WA
    [J]. SCIENCE, 2003, 301 (5641) : 1904 - 1908
  • [7] Generation of high curvature membranes mediated by direct endophilin bilayer interactions
    Farsad, K
    Ringstad, N
    Takei, K
    Floyd, SR
    Rose, K
    De Camilli, P
    [J]. JOURNAL OF CELL BIOLOGY, 2001, 155 (02) : 193 - 200
  • [8] Signaling and subcellular targeting by membrane-binding domains
    Hurley, JH
    Misra, S
    [J]. ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE, 2000, 29 : 49 - 79
  • [9] Implications of lipid microdomains for membrane curvature, budding and fission - Commentary
    Huttner, WB
    Zimmerberg, J
    [J]. CURRENT OPINION IN CELL BIOLOGY, 2001, 13 (04) : 478 - 484
  • [10] Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle
    Lee, EY
    Marcucci, M
    Daniell, L
    Pypaert, M
    Weisz, OA
    Ochoa, GC
    Farsad, K
    Wenk, MR
    De Camilli, P
    [J]. SCIENCE, 2002, 297 (5584) : 1193 - 1196