Chronic thromboembolic pulmonary hypertension (CTEPH): what do we know about it? A comprehensive review of the literature

被引:17
作者
Albani, Stefano [1 ,2 ]
Biondi, Federico [1 ,2 ]
Stolfo, Davide [1 ,2 ]
Lo Giudice, Francesco [3 ]
Sinagra, Gianfranco [1 ,2 ]
机构
[1] Univ Trieste, Div Cardiol, Cardiothorac Dept, Via Pietro Valdoni 7, I-34149 Trieste, Italy
[2] Univ Trieste, Postgrad Sch Cardiovasc Sci, Via Pietro Valdoni 7, I-34149 Trieste, Italy
[3] Hammersmith Hosp Imperial Coll NHS Trust, Pulm Hypertens Natl Serv, London, England
关键词
chronic thromboembolic pulmonary hypertension; pulmonary embolism; pulmonary endarterectomy; THROMBOTIC RISK-FACTORS; LONG-TERM EXTENSION; SURGICAL-MANAGEMENT; COMPUTED-TOMOGRAPHY; FOLLOW-UP; ENDARTERECTOMY; ANGIOPLASTY; EMBOLISM; DIAGNOSIS; ARTERIAL;
D O I
10.2459/JCM.0000000000000774
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Chronic thromboembolic disease (CTED), especially when associated with pulmonary hypertension (CTEPH), is a fearsome and under-diagnosed but potentially curable complication of pulmonary embolism, thanks to recent therapeutic options. Aspecific symptoms and signs make its diagnosis challenging, requiring clinicians to be ready to suspect its presence in patients with dyspnea of unknown origin or persistent symptoms after acute pulmonary embolism. The aim of this review is to provide an update to the general practitioner or the specialist physician on the state of the art regarding the epidemiology, pathophysiology and clinical management of chronic thromboembolic syndromes.
引用
收藏
页码:159 / 168
页数:10
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