PES Pathogens in Severe Community-Acquired Pneumonia

被引：23

作者：

Cilloniz, Catia ^{[1
]}

Dominedo, Cristina ^{[2
]}

Nicolini, Antonello ^{[3
]}

Torres, Antoni ^{[1
]}

机构：

[1] UB, Inst Invest Biomed August Pi I Sunyer IDIBAPS, Hosp Clin Barcelona, Dept Pneumol,Ciber Enfermedades Resp Ciberes, SGR 911, Barcelona 08036, Spain

[2] Univ Cattolica Sacro Cuore, Dept Anesthesiol & Intens Care Med, Fdn Policlin Univ A Gemelli, I-00168 Rome, Italy

[3] Hosp Sestri Levante, Resp Dis Unit, I-16039 Sestri Levante, Italy

来源：

MICROORGANISMS | 2019年 / 7卷 / 02期

关键词：

pneumonia; PES pathogens; severe pneumonia; community-acquired pneumonia; MULTIDRUG-RESISTANT PATHOGENS; HOSPITALIZED-PATIENTS; RISK-FACTORS; SEPSIS; STRATEGIES; GUIDELINES; MANAGEMENT; MORTALITY;

D O I：

10.3390/microorganisms7020049

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Worldwide, there is growing concern about the burden of pneumonia. Severe community-acquired pneumonia (CAP) is frequently complicated by pulmonary and extra-pulmonary complications, including sepsis, septic shock, acute respiratory distress syndrome, and acute cardiac events, resulting in significantly increased intensive care admission rates and mortality rates. Streptococcus pneumoniae (Pneumococcus) remains the most common causative pathogen in CAP. However, several bacteria and respiratory viruses are responsible, and approximately 6% of cases are due to the so-called PES (Pseudomonas aeruginosa, extended-spectrum beta-lactamase Enterobacteriaceae, and methicillin-resistant Staphylococcus aureus) pathogens. Of these, P. aeruginosa and methicillin-resistant Staphylococcus aureus are the most frequently reported and require different antibiotic therapy to that for typical CAP. It is therefore important to recognize the risk factors for these pathogens to improve the outcomes in patients with CAP.

引用

页数：13

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