3D carbon nanofiber microelectrode arrays fabricated by plasma-assisted pyrolysis to enhance sensitivity and stability of real-time dopamine detection

被引：7

作者：

Yi, Wenwen ^{[1
]}

Yang, Yuanyuan ^{[2
]}

Hashemi, Parastoo ^{[3
]}

Cheng, Mark Ming-Cheng ^{[1
]}

机构：

[1] Wayne State Univ, Dept Elect & Comp Engn, 5050 Anthony Wayne Dr, Detroit, MI 48202 USA

[2] Wayne State Univ, Dept Chem, 5101 Cass Ave, Detroit, MI 48202 USA

[3] Univ South Carolina, Dept Chem & Biochem, 631 Sumter St, Columbia, SC 29208 USA

来源：

BIOMEDICAL MICRODEVICES | 2016年 / 18卷 / 06期

基金：

美国国家科学基金会;

关键词：

Carbon nanofiber; Plasma-assisted pyrolysis; Dopamine; FSCV; SCAN CYCLIC VOLTAMMETRY; FIBER MICROELECTRODES; C-MEMS; ELECTROCHEMICAL APPLICATIONS; GLUCOSE SENSORS; PHOTORESIST; ELECTRODES; MICROARRAYS; FILMS; INTEGRATION;

D O I：

10.1007/s10544-016-0136-1

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

In this paper, we have fabricated 3D carbon nanofiber microelectrode arrays (MEAs) with highly reproducible and rich chemical surface areas for fast scan cyclic voltammetry (FSCV). Carbon nanofibers are created from negative photoresist by a new process called dual O-2 plasma-assisted pyrolysis. The proposed approach significantly improves film adhesion and increases surface reactivity. We showcase our sensor's compatibility with FSCV analysis by demonstrating highly sensitive and stable FSCV dopamine measurements on a prototype 4-channel array. We envision with proper surface fuctionalization the 3D carbon nanofiber MEA enable sensitive and reliable detection of multiple neurotransmitters simultaneously.

引用

页数：9

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