Human in vivo-differentiated monocyte-derived dendritic cells

被引:49
作者
Tang-Huau, Tsing-Lee [1 ,2 ]
Segura, Elodie [1 ]
机构
[1] PSL Res Univ, Inst Curie, INSERM, U932, 26 Rue Ulm, F-75005 Paris, France
[2] Sanofi, Breakthrough Lab, 1 Impasse Ateliers, F-94400 Vitry Sur Seine, France
关键词
Monocyte; Dendritic cell; Inflammation; Auto-immune disease; Cancer; 6-SULFO LACNAC; STEADY-STATE; MACROPHAGES; DISTINCT; POPULATION; RESPONSES; REVEALS; LUNG; ACCUMULATION; PRECURSORS;
D O I
10.1016/j.semcdb.2018.02.018
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
When entering tissues, monocytes can differentiate into cells that share morphological and functional features with either dendritic cells (DC) or macrophages. Monocyte-derived DC have been observed in humans at mucosal tissues and in inflammatory settings, where they are usually referred to as "inflammatory DC". In this chapter, we review recent studies on the characterization of these cells in humans. We also discuss nomenclature and examine the criteria defining in vivo-differentiated human mo-DC. (C) 2018 Elsevier Ltd. All rights reserved.
引用
收藏
页码:44 / 49
页数:6
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